Resilience: surviving and thriving in the paediatric workplace.

The health of the medical workforce, within the UK, has been described as an unmet public health need. Reports of stress, burnout and ill health are continuing to rise. Burnout is when meaningful and challenging work becomes unpleasant and unfulfilling; energy turns into exhaustion; enthusiasm turns into cynicism and efficacy turns into ineffectiveness.

A paediatric case of macro aspartate aminotransferase.

Macroenzymes are enzymes in plasma that have a higher molecular mass than the corresponding enzyme normally present under (patho) physiological conditions. Macro species have been described for most routinely measured enzymes, but with only a few reports of macro species with aspartate aminotransferase (AST), and in particular very few reports in children and adolescents. Routine biochemical analysis in a 15-year-old girl presenting with lower back pain revealed an isolated raised AST as part of a liver function test profile.