Ultrasensitive detection of antimicrobial resistance genes using hybridization chain reaction employing carbon dots.

One of the top 10 global concerns include AntiMicrobial Resistance (AMR), which warrants the need to develop materials and methods for detection of AMR genes. Here, we propose a proof-of-concept approach for selective and ultrasensitive detection of AMR gene employing fluorescent carbon dots. Waste pistachio shell derived green emissive carbon dots (PCDs) with a high quantum yield of 24 were prepared hydrothermal carbonization process and characterised using microscopic and spectroscopic techniques.

Structural DNA nanotechnology at the nexus of next-generation bio-applications: challenges and perspectives.

DNA nanotechnology has significantly progressed in the last four decades, creating nucleic acid structures widely used in various biological applications. The structural flexibility, programmability, and multiform customization of DNA-based nanostructures make them ideal for creating structures of all sizes and shapes and multivalent drug delivery systems. Since then, DNA nanotechnology has advanced significantly, and numerous DNA nanostructures have been used in biology and other scientific disciplines.