Publications by authors named "Sanjana B Singh"
Context: The role of genetic factors in the development of diabetic retinopathy is evident from the fact that only 50% of patients with the non-proliferative type of diabetic retinopathy progress to proliferative diabetic retinopathy. Though the K469E polymorphism of the ICAM-1 (Intercellular Adhesion Molecule-1) gene is known to increase the risk of developing Diabetic Retinopathy (DR) among Type 2 diabetic patients, its role in the development of severe DR has not been extensively studied.
Aim: Hence, we aimed to determine the risk due to association of K469E polymorphism of ICAM-1 gene and sight threatening diabetic retinopathy.
Article Synopsis
- A 13-year-old girl diagnosed with IRVAN struggled with central vision loss for 10 months and had poor responses to previous steroid treatments.
- She was initially treated with intravitreal dexamethasone and oral Mycophenolate Mofetil but showed only temporary improvement.
- The patient's condition was successfully managed with a new combination therapy of Adalimumab and Azathioprine, marking the first documented case of this approach for IRVAN treatment.
Hemangiopericytoma rarely affects the central nervous system (CNS) and usually presents to neurologists with neurological symptoms. We report a rare case of large CNS hemangiopericytoma which presented to an ophthalmologist with only signs of mild defective vision and papilledema.
View Article and Find Full Text PDF