Publications by authors named "Sani Awwalu"
Background: Helicobacter Pylori infection occurs worldwide. Patients with Sickle Cell Disease (SCD) may present with abdominal symptoms due to different pathophysiological mechanisms. SCD patients are predisposed to infections due to immune deficiency, abdominal symptoms like dyspepsia and recurrent abdominal pain have been associated with infection.
View Article and Find Full Text PDFSickle cell disease affects about 150,000 births annually in Nigeria. Early diagnosis is hampered by factors such as centralized and urban localization of laboratories, high cost of diagnostic equipment and inadequate skilled manpower to operate them. The need for a low-cost, portable, easy-to-use diagnostic test for sickle cell disease is critical, especially in resource-poor countries.
View Article and Find Full Text PDFBackground: Safe, timely red blood cell transfusion saves lives and chronic transfusion therapy (CTT) prevents or limits morbidities such as stroke, therefore improving quality of life of patients with sickle cell disease (SCD).
Methods: This questionnaire-based study assessed the ability of sickle cell centers in Nigeria to provide safe blood to patients with SCD between March and August 2014.
Results: Out of the 73 hospitals contacted, responses were obtained from 31.
Article Synopsis
- The World Health Organisation classifies myeloproliferative neoplasm (MPN) into two categories: BCR-ABL positive chronic myeloid leukaemia (CML Ph(+)) and Ph(-) MPN, with the JAK2 V617F mutation being common in the latter.
- The JAK2 mutation occurs in about 50% of cases of primary myelofibrosis, while earlier findings indicated that JAK2 and BCR-ABL mutations usually don't occur together.
- However, new evidence shows that patients can have both mutations, especially after receiving treatment with tyrosine kinase inhibitors (TKIs), as illustrated by a case of a 60-year-old male exhibiting both types of