Publications by authors named "Sangwon Son"
Article Synopsis
- Animals show phenotypic plasticity through gene-environment interactions, and this study explores genetic factors affecting synaptic function during development in the nematode C. elegans.
- Researchers found that while the dauer larval stage (which is stress-resistant) typically has reduced sensitivity to many chemicals, it is unusually sensitive to the cholinesterase inhibitor aldicarb.
- The gene cyp-34A4 (or dach-1), which encodes a cytochrome P450, is key in modulating this sensitivity and also plays roles in regulating quiescence and stress resistance in dauer larvae, highlighting its importance in developmental plasticity.
Cilia are important for the interaction with environments and the proper function of tissues. While the basic structure of cilia is well conserved, ciliated cells have various functions. To understand the distinctive identities of ciliated cells, the identification of cell-specific proteins and its regulation is essential.
View Article and Find Full Text PDFMembrane integrity is critical for cell survival, defects of which cause pathological symptoms such as metabolic diseases. In this study, we used ethanol sensitivity of the nematode Caenorhabditis elegans to identify genetic factors involved in membrane integrity. InC.
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