The use of muscle extracellular matrix (MEM) and SCPC bioceramic for bone augmentation.

Background: Bone augmentation is a challenging problem in the field of maxillofacial surgery.

Objective: In this study, we prepared and evaluated muscle extracellular matrix (MEM) after adding silica calcium phosphate composite (SCPC) seeded with human bone marrow mesenchymal cells (hBMSCs). We then investigated bone augmentation in vivo using the prepared MEM-SCPC.