Publications by authors named "Sangita Saha"
Context: Nocturnal enuresis (NE) is a very common problem in childhood. The prevalence rate varies from 3.5% to 56.
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- - The study investigated the potential of exopolysaccharides (EPSs) from endophytic fungi to counteract health issues caused by arsenic (As(III)), focusing on their effects on metabolic and reproductive problems.
- - Two fungi (Diaporthe arengae and Fusarium proliferatum) were used to extract EPSs, which demonstrated abilities like reducing oxidative stress, correcting hormonal imbalances, and influencing apoptosis-related markers after exposure to arsenic.
- - The research suggested that the components of the EPSs might interact with androgen receptors, limiting their activity and highlighting EPSs as promising candidates for new treatments targeting arsenic toxicity.
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- A study investigated the effectiveness of individualized homeopathic medicinal products (IHMPs) compared to placebos for improving health-related quality of life in individuals suffering from post-COVID-19 conditions, with up to 80% of infected individuals experiencing ongoing symptoms.* -
- Conducted at a medical college in India, the trial involved 60 participants divided into two groups: one receiving IHMPs plus care and the other receiving placebos plus care. The study tracked health outcomes over three months using established assessment tools.* -
- Results showed that IHMPs significantly outperformed placebos in reducing post-COVID-19 symptoms, with notable improvements in both primary and secondary outcome measures, suggesting promise for homeopathic treatments in future
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- The study aimed to systematically investigate symptoms associated with commonly prescribed homeopathic medicines using Bayesian statistics for more accurate likelihood ratios (LR).
- Conducted over 21 months with 1,954 patients, the research utilized the ORIDL scale to measure treatment outcomes and calculated LRs for four specific symptoms linked to six selected homeopathic remedies.
- Findings revealed high LR+ scores for symptoms like "dyspepsia from business anxiety" and "burning pain relieved by heat," supporting existing homeopathic literature, but emphasized the need for further research to confirm results in larger populations.
Context: Pre-diabetes is a significant public health problem worldwide. India has a very high rate of progression from pre-diabetes to diabetes, 75-78 per thousand persons per year.
Objective: To study the efficacy of individualized homeopathic medicinal products (HMPs) against placebos in preventing the progression from pre-diabetes to diabetes.
Introduction: The coronavirus disease 2019 (COVID-19) is leading to unknown and unusual health conditions that are challenging to manage. Post-COVID-19 fatigue is one of those challenges, becoming increasingly common as the pandemic evolves, as it impairs the quality of life of an individual. This trial attempts to identify the preliminary evidence of the efficacy of individualized homeopathic medicines (IHMs) against placebos in the treatment of post-COVID-19 fatigue in adults.
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- Usability is how easy it is to use a website, and different things can make it better or worse.
- This study created a model that predicts how well users can complete tasks on websites by looking at 17 important features.
- They tested this model on 20 websites and found out that it can predict task efficiency with about 90% accuracy, showing most features really matter.
Introduction: Individualized homeopathy (IH) in atopic dermatitis (AD) remained under-researched.
Objective: We aimed at evaluating efficacy of IH in AD.
Methods: A double-blind, randomized, placebo-controlled, short-term, preliminary trial was conducted in an Indian homeopathy hospital.
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- A study was conducted to evaluate the effects of individualized homeopathic treatments versus placebos on patients with warts, aiming to lay groundwork for future research.
- The double-blind trial involved 60 participants and measured changes in wart size and quantity, as well as quality of life, over three months, revealing significant improvements within the homeopathy group but not between groups.
- Ultimately, the results were inconclusive regarding the effectiveness of homeopathy, although there was a slight tendency favoring homeopathy without any reported negative side effects.
There is lack of studies assessing the preference of Indian patients for integration of homeopathy into standard therapy settings. The objectives of this study were to examine the knowledge, attitudes, and practice of homeopathy among Indian patients already availing homeopathy treatment and its integration into mainstream healthcare. A cross-sectional survey was conducted among adult patients attending the out-patients of the four government homeopathic hospitals in West Bengal, India.
View Article and Find Full Text PDFThe authors aimed to document prescriptions and clinical outcomes in routine homeopathic practice to short list promising areas of targeted research and efficacy trials of homeopathy in obstetrics and gynecology (O&G). Three homeopathic physicians participated in methodical data collection over a 3-month period in the O&G outpatient setting of The Calcutta Homeopathic Medical College and Hospital, West Bengal, India. A specifically designed Excel spreadsheet was used to record data on consecutive appointments, including date, patient identity, socioeconomic status, place of abode, religion, medical condition/complaint, whether chronic/acute, new/follow-up case, patient-assessed outcome (7-point Likert scale: -3 to +3), prescribed homeopathic medication, and whether other medication/s was being taken for the condition.
View Article and Find Full Text PDFObjective: To our knowledge, prescription of homeopathic medicines by homeopathic undergraduate students has not been studied before though it may possess serious implications. We aimed to determine the practice and attitudes of prescription by homeopathic undergraduate students.
Methods: A cross-sectional study was carried out involving all the students from four government homeopathic schools of West Bengal, India.
Pseudogenes are defined as non-functional relatives of genes whose protein-coding abilities are lost and are no longer expressed within cells. They are an outcome of accumulation of mutations within a gene whose end product is not essential for survival. Proper investigation of the procedure of pseudogenization is relevant for estimating occurrence of duplications in genomes.
View Article and Find Full Text PDFSelective modulators of GABA(A) alpha(3) (gamma amino butyric acid alpha(3)) receptor are known to alleviate the side effects associated with nonspecific modulators. A follow up study was undertaken on a series of functionally selective phthalazines with an ideological credo of identifying more potent isofunctional chemotypes. A bioisosteric database enumerated using the combichem approach endorsed mining in a lead-like chemical space.
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