One-pot synthesis of glycyrrhetic acid polyglycosides based on grafting-from method using cyclic sulfite.

Glycyrrhetic acid polyglycosides were synthesized in one-pot via cationic ring-opening condensation polymerization of cyclic sulfite () initiated by glycyrrhetic acid as an aglycon. Sulfite worked as a practical monomer for the preparation of (1 → 2)-linked polysaccharide skeletons. The chemical stability of was evaluated by the comparison of thermodynamic parameters with those of conventional epoxide ().

Cross-sectional population-based study of knowledge, attitudes, and practices regarding HIV/AIDS in Dakshina Kannada district of Karnataka, India.

Objective: To assess HIV/AIDS-related knowledge, attitudes, and practices among the general population in South India.

Methods: The 1669 participants (834 males, 835 females) aged 19-49 years were surveyed using a stratified 2-stage random sampling design with probability proportional to size.

Results: Although 54% of participants knew that AIDS is caused by "HIV" virus and 44% could correctly identify all modes of transmission, 52% believed in one or more myths, 41% did not know that condoms can prevent HIV, and 18% had not heard of a condom.