Previous studies have shown that common variants of the gene coding for FK506-binding protein 51 (), a critical regulator of glucocorticoid sensitivity, affect vulnerability to stress-related disorders. In a previous report, rs1360780 was identified as a functional variant because of its effect on gene methylation. Here we report evidence for a novel functional allele, rs3800373.
View Article and Find Full Text PDFIntroduction: A motor vehicle collision (MVC) is one of the most common life-threatening events experienced by individuals living in the USA. While most individuals recover following MVC, a significant proportion of individuals develop adverse post-traumatic sequelae such as post-traumatic stress disorder or persistent musculoskeletal pain. Adverse post-traumatic sequelae are common, morbid and costly public health problems in the USA and other industrialised countries.
View Article and Find Full Text PDFWe obtained recommendations for a graphical user interface (GUI) design for a new medical monitoring system. Data were obtained from 26 combat-experienced medics. Volunteers were briefed on the medical monitoring system.
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