Publications by authors named "SangKeun Park"

Article Synopsis
  • Decreasing blood donation rates have created a need for alternative sources, leading to the exploration of genetically engineered pig red blood cells (pRBCs), particularly triple-gene knockout (TKO) versions, for human transfusion compatibility.
  • In a study involving nonhuman primates, both wild-type (WT) and TKO-pRBC transfusions significantly improved red blood cell counts initially, but triggered the body's immune response, leading to rapid antibody production and liver function impairment.
  • While initial hematological improvements were noted on the first day post-transfusion, both pRBC types showed diminished circulation benefits and increased adverse reactions upon subsequent transfusions, raising concerns about their long-term efficacy in humans.
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The decline in blood donation rates and the ongoing shortage of blood products pose significant challenges to medical societies. One potential solution is to use porcine red blood cells (pRBCs) from genetically modified pigs as an alternative to human red blood cells (hRBCs). However, adverse immunological reactions remain a significant obstacle to their use.

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Background: Accurately predicting the demand for blood transfusions is crucial for blood banks. Given the potential for emergency situations, it is imperative that blood banks maintain a sufficient inventory of blood products. In this study, we examined the use of perioperative transfusions in patients undergoing elective kidney transplants.

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Background: "Sunken eyelid" is a term used to describe a deeply sunken area between the upper eyelid and upper edge of the orbital bone. The condition frequently is accompanied by blepharoptosis. Correction of a "sunken eyelid" generally is performed with a fat graft.

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Background: The frontalis sling procedure is a useful approach for correcting severe blepharoptosis. However, blepharoptosis often recurs after corrective surgery using the tensor fascia lata. Good results without recurrence after a modified Fox method were obtained using the palmaris longus tendon.

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