Complete genome sequences of strains ASE2 and ASE4 generated by PacBio sequencing.

strains ASE2 and ASE4 were isolated from the soil of a lettuce farm in Salinas, California, in 2020. Their complete genome sequences were generated by the PacBio Sequel II platform. They both consist of a single circular chromosome without plasmids.

INSANet: INtra-INter Spectral Attention Network for Effective Feature Fusion of Multispectral Pedestrian Detection.

Pedestrian detection is a critical task for safety-critical systems, but detecting pedestrians is challenging in low-light and adverse weather conditions. Thermal images can be used to improve robustness by providing complementary information to RGB images. Previous studies have shown that multi-modal feature fusion using convolution operation can be effective, but such methods rely solely on local feature correlations, which can degrade the performance capabilities.

Testing the bipolar assumption of Singer-Loomis Type Deployment Inventory for Korean adults using classification and multidimensional scaling.

In this study, we explored whether the Korean version of Singer Loomis Type Deployment Inventory II (K-SLTDI) captures the opposing tendencies of Jung's theory of psychological type. The types are Extroverted Sensing, Extroverted Intuition, Extroverted Feeling, Extroverted Thinking, Introverted Sensing, Introverted Intuition, Introverted Feeling, and Introverted Thinking. A nationwide online survey was conducted in South Korea.

Complete genome sequence of ASE1 generated by PacBio sequencing.

We report the complete genome sequence of ASE1 generated by the PacBio Sequel II platform. This bacterium was isolated from the soil of a lettuce farm in Salinas, CA, USA, in 2020. The genome consists of a single circular chromosome of 5,021,820 bp with a 52.

Identification of Terpene Compositions in the Leaves and Inflorescences of Hybrid Species Using Headspace-Gas Chromatography/Mass Spectrometry.

Although cannabidiol and tetrahydrocannabinol in species exert their pharmacological effects via the endocannabinoid system, it is believed that other phytochemicals, particularly terpenes, can modulate therapeutic outcomes through the entourage effect. Therefore, to gain a better understanding of the pharmacological effects of , obtaining information on phytochemical compositions, including mono-, di-, and sesqui-terpenes in species is essential. Applying a sophisticated analytical method is indispensable.

Effective Interaction between Homo- and Heteropolymer Block of Poly(-butyl acrylate)--poly(methyl methacrylate--styrene) Diblock Copolymers.

We investigated the segregation behavior of a molten diblock copolymer, poly(-butyl acrylate)--poly(methyl methacrylate--styrene) (PBA--P(MMA--S)), wherein styrene (S) is incorporated as a comonomer in the second block to modulate the effective interaction between homopolymer and a random copolymer block. The temperature dependence of the effective interaction parameter χeff between -butyl acrylate (BA) and the average monomer of the MMA--S random block was evaluated from small-angle X-ray scattering (SAXS) analysis using the random phase approximation (RPA) approach. The calculated χeff, as a function of the styrene fraction in the random copolymer block, shows a good agreement with the mean-field binary interaction model.

Small-Angle X-ray Scattering Analysis on the Estimation of Interaction Parameter of Poly(-butyl acrylate)--poly(methyl methacrylate).

The temperature dependence of the Flory-Huggins interaction parameter χ for poly(-butyl acrylate)--poly(methyl methacrylate) (PBA--PMMA) was quantified from small-angle X-ray scattering (SAXS) analysis using random phase approximation (RPA) theory. It was found from the χ estimation (χ=0.0103+14.

Consumption of Antioxidant-Rich "Cerrado" Cashew Pseudofruit Affects Hepatic Gene Expression in Obese C57BL/6J High Fat-Fed Mice.

The pseudofruit of Rizzini, "Cerrado" cashew pulp, has been described as rich in flavonoids, phenolic compounds, and vitamin C. The objective of this work was to evaluate the beneficial health effects seen with the addition of "Cerrado" cashew pulp (CP) to an obesogenic high fat diet provided to C57BL/6J male mice. In week 9, the HF-fed group had a significantly higher baseline glucose concentration than the LF- or HF+CP-fed groups.

Robust Three-Dimensional (3D) Expansion of Bovine Intestinal Organoids: An In Vitro Model as a Potential Alternative to an In Vivo System.

Intestinal organoids offer great promise for disease-modelling-based host-pathogen interactions and nutritional research for feed efficiency measurement in livestock and regenerative medicine for therapeutic purposes. However, very limited studies are available on the functional characterisation and three-dimensional (3D) expansion of adult stem cells in livestock species compared to other species. Intestinal crypts derived from intestinal organoids under a 3D culture system from the small intestine in adult bovine were successfully established and characterised for functionality testing, including the cellular potentials and genetic properties based on immunohistochemistry, immunocytochemistry, epithelial barrier permeability assay, QuantSeq 3' mRNA-Seq.

DIGREM: an integrated web-based platform for detecting effective multi-drug combinations.

Motivation: Synergistic drug combinations are a promising approach to achieve a desirable therapeutic effect in complex diseases through the multi-target mechanism. However, in vivo screening of all possible multi-drug combinations remains cost-prohibitive. An effective and robust computational model to predict drug synergy in silico will greatly facilitate this process.

A two-stage approach of gene network analysis for high-dimensional heterogeneous data.

Gaussian graphical models have been widely used to construct gene regulatory networks from gene expression data. Most existing methods for Gaussian graphical models are designed to model homogeneous data, assuming a single Gaussian distribution. In practice, however, data may consist of gene expression studies with unknown confounding factors, such as study cohort, microarray platforms, experimental batches, which produce heterogeneous data, and hence lead to false positive edges or low detection power in resulting network, due to those unknown factors.

Integrative Analysis of Gene Networks and Their Application to Lung Adenocarcinoma Studies.

The construction of gene regulatory networks (GRNs) is an essential component of biomedical research to determine disease mechanisms and identify treatment targets. Gaussian graphical models (GGMs) have been widely used for constructing GRNs by inferring conditional dependence among a set of gene expressions. In practice, GRNs obtained by the analysis of a single data set may not be reliable due to sample limitations.

The Transition from Thin Basement Membranes to Typical Alport Syndrome Morphology in Children.

Some children with thin basement membranes (TBM) turn out to have Alport syndrome (AS). In our population of 58 children initially diagnosed with TBM, three were eventually diagnosed with AS. As a group, these three were first biopsied at a younger age, and had gross rather than microscopic hematuria.

Sparse estimation of gene-gene interactions in prediction models.

Current assessment of gene-gene interactions is typically based on separate parallel analysis, where each interaction term is tested separately, while less attention has been paid on simultaneous estimation of interaction terms in a prediction model. As the number of interaction terms grows fast, sparse estimation is desirable from statistical and interpretability reasons. There is a large literature on sparse estimation, but there is a natural hierarchy between the interaction and its corresponding main effects that requires special considerations.

Sunlight-induced self-healing of a microcapsule-type protective coating.

Photopolymerization behavior of a methacryloxypropyl-terminated polydimethylsiloxane (MAT-PDMS) healing agent was investigated in the presence of benzoin isobutyl ether (BIE) photoinitiator by Fourier transform infrared (FT-IR) spectroscopy. MAT-PDMS and BIE were microencapsulated with urea-formaldehyde polymer. The surface and shell morphology of the microcapsules was investigated by scanning electron microscopy (SEM).

Effect of homopolymer molecular weight on order-order transition in block copolymer and homopolymer blends.

The order-order transition temperature (T(OOT)) in blends of poly(styrene-b-isoprene-b-styrene) (S-I-S) triblock copolymer and polyisoprene (PI) homopolymer was investigated by using synchrotron small-angle X-ray scattering (SAXS). Pure triblock copolymer undergoes an order-order transition (OOT) from hexagonally ordered cylinder (HEX) to body centered cubic (BCC) phases. In order to investigate the effect of the molecular weight of the added homopolymer on T(OOT) of the triblock copolymer, various low-molecular-weight PI homopolymers were studied.

The diagnostic value of endoprobe for small esophageal leiomyomas derived from the muscularis mucosae.

Esophageal leiomyoma derived from the muscularis mucosae (MM) is a rare condition, and the optimal modality for diagnosis and treatment is controversial. Endoscopic ultrasonography can provide an accurate image of esophageal layer structure, providing information on lesion suitability for potential endoscopic therapy. We attempted to investigate the diagnostic value of a transendoscopic balloon-tipped miniature ultrasonic endoprobe for small esophageal leiomyomas derived from MM.

Post-infectious irritable bowel syndrome in patients with Shigella infection.

Background And Aims: Bacterial gastroenteritis has been known as a risk factor of irritable bowel syndrome (IBS). Several risk factors of post-infectious IBS (PI-IBS) have been documented. The aims of this study were to verify the role of bacterial gastroenteritis in the development of IBS and the risk factors for the development of PI-IBS.

Investigation into the effects of mosapride on motility of Guinea pig stomach, ileum, and colon.

Mosapride citrate (Mosapride) is a new prokinetic agent that enhances the gastrointestinal (GI) motility by stimulation of 5-HT4 receptors. This agent stimulates acetylcholine release from enteric cholinergic neurons in the GI wall. It was reported in several studies that mosapride selectively enhanced the upper, but not lower, GI motor activity.