Publications by authors named "SangHee Woo"

This study conducted real-time monitoring of size-resolved particle concentrations ranging from 9 nm to 10 μm simultaneously at four sites on the park ground and the roof of a five-story apartment buildings in the upwind and downwind areas of the Olympic Expressway next to apartment complex areas of Seoul, Korea. Using a positive matrix factorization model for source apportionment, eight factors were resolved at each monitoring site: four exhaust emissions of vehicles, one non-exhaust emission of vehicle, two regional sources, and one unknown source. After categorizing monitoring data into three cases by wind conditions, impact and contribution of each vehicle-related source on the local road to the roadside pollution was quantified and characterized by subtracting the urban background concentrations.

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The adenovirus detection rate is <10% throughout the year in South Korea; however, during the summer of 2023, it showed an unusual increase. We analyzed the adenovirus detection rate using data from the Korea Respiratory Integrated Surveillance System before and after coronavirus disease (COVID-19) collected from 2019 to week 36 of 2023. Before the COVID-19 outbreak in 2019, the mean detection rate was 8.

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Article Synopsis
  • The COVID-19 pandemic led to a significant decline in the incidence of various respiratory viruses due to health measures, but these infections returned as restrictions were lifted, particularly in Korean children.
  • A nationwide surveillance study analyzed respiratory virus data from children and adolescents from January 2017 to June 2023, comparing detection rates and age distributions before and after the pandemic.
  • Findings showed a drop in overall virus detection during the pandemic, with a notable increase in co-detections post-pandemic; unique outbreaks of certain viruses like PIV and HMPV occurred out of season, and the average age of affected children increased significantly in 2023 compared to pre-pandemic years.
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  • The Korea Disease Control and Prevention Agency (KDCA) is conducting genomic surveillance to track and analyze SARS-CoV-2 variants in South Korea using over 102,000 patient samples.
  • COVID-19 variant waves emerged first internationally and then spread domestically, with key variants including B.41 in 2020, Delta in 2021, and various Omicron sub-lineages in 2022.
  • The KDCA has been proactive in detecting new variants before widespread outbreaks, highlighting the need for ongoing monitoring to safeguard public health against emerging threats.
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In urban areas, particulate matter emitted from vehicles directly affects the health of citizens near roads. Thus, in this study, particle size distribution was measured by the horizontal and vertical distances along a highway road with heavy traffic to characterize the dispersion phenomena of particulate matter emitted from vehicles. In addition, the contribution of pollution sources was analyzed using a source-receptor model.

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Electric vehicles (EVs) are regarded as zero emission vehicles due to the absence of exhaust emissions. However, they still contribute non-exhaust particulate matter (PM) emissions, generated by brake wear, tire wear, road wear, and resuspended road dust. In fact, because EVs are heavier than internal combustion engine vehicles (ICEVs), their non-exhaust emissions are like to be even higher.

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Tires generally wear out due to the friction between the tire and the road surface. Minimizing tire wear could reduce the non-exhaust particulate matter (PM) emissions from tires. Typically, tire treadwear grade can be used as an indicator of PM emissions from tires.

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Physical friction between a tire and the road surface generates tire wear particles (TWPs), which are a source of microplastics and particulate matter. This study investigated the trends of chemical leaching from TWPs depending on the treadwear rating of the tire. A road simulator was used to produce TWPs from tires with various treadwear ratings.

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Condensable particulate matter (CPM) corresponds to primary particulate matter ≤2.5 μm (PM) obtained through the condensation of gaseous air pollutants caused by temperature drops in the atmosphere. The internal combustion of vehicle engines can produce CPM because of the condensable compounds in the exhaust gas.

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We report the rapid emergence of severe acute respiratory syndrome coronavirus 2 lineages B.1.619 and B.

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Article Synopsis
  • As COVID-19 continues, reinfections are likely to rise, but confirmation is challenging due to the need for whole-genome sequencing to assess genetic differences between infections.* -
  • In a study of four suspected reinfection cases in young patients (ages 10-29), researchers found that only two were confirmed reinfections, both involving the Epsilon variant.* -
  • The study highlights the increasing potential for reinfections amid the ongoing pandemic and emphasizes the importance of continuous monitoring of COVID-19 cases.*
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Article Synopsis
  • The study investigates how genomic epidemiology was used to analyze the spread of SARS-CoV-2 in South Korea by examining viral genome sequences from over 2,000 cases during 2020.
  • The analysis found that while most imported cases from travelers did not spread widely, four viral subgroups caused local outbreaks, which were eventually controlled after enhanced social distancing measures were implemented.
  • The results suggest that South Korea's traveler quarantine and social distancing strategies were effective in reducing virus spread, but further improvements are needed to fully control variants and future pandemics.
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Article Synopsis
  • - A novel beta-coronavirus, SARS-CoV-2, emerged in December 2019, leading to a global outbreak and prompting genomic surveillance in South Korea.
  • - The Korea Disease Control and Prevention Agency sequenced 2,488 SARS-CoV-2 samples over a year, noting a shift in dominant virus clades from S and V to GH by March 2020.
  • - The study found that quarantining international travelers effectively limited the spread of multiple SARS-CoV-2 variants within Korea.
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  • The study investigates the potential transmission of SARS-CoV-2, the virus causing COVID-19, through non-respiratory routes such as serum, urine, and stool in hospitalized patients.
  • Out of 74 patients, SARS-CoV-2 was detected in 15 samples, with the highest detection rate in stool (10.1%).
  • The findings suggest that although the virus can be detected in non-respiratory samples, it could not be isolated, indicating a low risk of transmission through these routes.
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Understanding characteristics of diurnal particle concentration variation in an underground subway tunnel is important to reduce subway passengers' exposure to high levels of toxic particle pollution. In this study, real-time particle monitoring for eight consecutive days was done at a shelter located in the middle of a one-way underground subway tunnel in Seoul, Republic of Korea, during the summer of 2015. Particle mass concentration was measured using a dust monitor and particle number concentration using an optical particle counter.

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In Korea, an increasing number of people attempt to evade military conscription by posing as mental health patients. To verify the authenticity of mental illness, there is a need to detect wide range of psychoactive agents in biological specimens of conscription candidates. In this study, we developed and validated a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for simultaneous determination of 18 psychoactive agents and 6 metabolites in human plasma.

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In recent years, the inappropriate use of antipsychotics by young Korean men has become a social problem. As military service exemptions are given for mental illness, some men pose as mental health patients to avoid military service. In order to verify the authenticity of mental illnesses, we developed simultaneous analytical methods for the detection of 15 antipsychotics and 2 of their metabolites in hair using liquid chromatography-tandem mass spectrometry (LC-MS/MS) analysis.

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The unintended influence of exhaust plumes emitted from a vehicle ahead to on-road air quality surveying data measured with a mobile laboratory (ML) at 20-40 km h in dense traffic areas was investigated by experiment and life-sized computational fluidic dynamics (CFD) simulation. The ML equipped with variable sampling inlets of five columns by four rows was used to measure the spatial distribution of CO and NO concentrations when following 5-20 m behind a sport utility vehicle (SUV) as an emitter vehicle equipped with a portable emission monitoring system (PEMS). The PEMS measured exhaust gases at the tailpipe for input data of the CFD simulations.

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In this study, we measured the size distribution of particles ranging in size from 5.6 to 560 nm that were emitted between brake disks and pads under various braking conditions to observe and analyze changes to the resulting particle size distribution over braking time. A peak of 178-275 nm (200 nm peak) was observed in all braking conditions.

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In 2014, an H5N8 outbreak of highly pathogenic avian influenza (HPAI) occurred in South Korea. The H5N8 strain produced mild to moderate clinical signs and mortality rates in commercial chicken farms, especially Korean native chicken farms. To understand the differences between their pathogenicity in SPF chicken and Korean native chicken.

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A sensitive and specific high-performance liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed for the determination of Grayanotoxin I (GTX I) and Grayanotoxin III (GTX III) in rat whole blood. Grayanotoxins (GTXs) and clindamycin as internal standard (IS) were extracted from rat blood via solid-phase extraction using PEP solid-phase extraction cartridges. Chromatographic separation of the analytes was achieved on a Kinetex C18 (100 × 2.

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