To test the suitability of cell bioassay as a tool for screening the toxicological risk of dioxin-like compounds, an in vitro toxicity assay was performed using samples obtained from small sized Korean waste incineration plants. Stress-related gene expression, cell viability, apoptosis, DNA damage and cell cycles were investigated as toxicological indicators of the polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDDs/DFs) exposed human bronchial epithelial cell, Beas-2B. Of the stress-related genes, the expressions of the aryl hydrocarbon receptor (AhR), cytochrome P450 (CYP) and p53 genes were most significantly induced by exposure to PCDDs/DFs.
View Article and Find Full Text PDFTo investigate the leaching characteristic of persistent organic pollutants (POPs), such as non-ortho and mono-ortho substituted chlorobiphebyls (dioxin-like PCBs), polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDDs/DFs), in leachate from municipal solid waste (MSW) landfill sites containing incineration residues, raw leachate samples were collected twice from 12 selected MSW landfill sites. The samples were divided into their liquid and solid phases using GF/B (pore size 1.0 microm), and the concentrations of POPs then determined.
View Article and Find Full Text PDFThe properties of dissolved organic matter (DOM) in the leachates discharged from lysimeters and landfill sites containing municipal solid waste incineration residues (MSWIRs) were studied. DOM samples were divided into hydrophobic acid, base, neutral (Hpo-A, Hpo-B, Hpo-N) and hydrophilic (Hpi) fractions using the fractionation method employing DAX-8 resin. Hpi was the smallest fraction of all the raw leachate samples.
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