Publications by authors named "Sang-Kyun Park"

Article Synopsis
  • The COVID-19 pandemic has caused many older adults to become physically inactive, leading to declines in fitness and body composition, particularly affecting immune system health.
  • A study comparing two groups of older adults—one that continued physical activity and another that did not—found significant differences in fitness levels, body composition, and markers of inflammation.
  • Maintaining physical activity during lockdown helped the active group preserve fitness levels, reduce fat mass, and support immune function compared to those who were inactive.
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This study aimed to identify neuroendocrine substances and natural killer (NK) cells, including their subsets and receptors, to determine whether phytoncides scented in an urban hospital could help improve stress in cancer survivors. Fifty-five gynecological cancer survivors were assigned to either the control group (CG, n=28) or phytoncide group (PTG, n=27). The PTG meditated by lying down in a space scented with phytoncide for 1 hr a day, 5 days a week for 8 weeks.

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Background: Peripheral facial nerve palsy (PFNP) is a cranial neuropathy that occurs when the seventh facial nerve is damaged. PFNP seriously affects patients' quality of life, and approximately 30% of patients suffer from sequelae, such as unrecovered palsy, synkinesis, facial muscle contracture, and facial spasm. Many studies have confirmed the effectiveness of acupuncture for the treatment of PFNP.

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This study aimed to examine whether compared with a program without walking, intervention programs with three types of walking can improve the muscle property and immunocytes in elderly women. Thirty-two subjects were randomly assigned to control group (CON), slow walking group (SWG), moderate walking group (MWG), and fast walking group (FWG). Three types of walking on treadmill were 30 min a day, 5 days/wk for 12 weeks.

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Article Synopsis
  • Peripheral facial nerve palsy primarily refers to lower motor neuron issues in the facial nerve, with idiopathic Bell's palsy being the leading cause, representing 60-70% of cases, though its exact cause is still unclear.
  • Recent studies have used functional neuroimaging to investigate changes in brain function in Bell's palsy patients, but findings have been inconsistent due to varying methodologies.
  • This review aims to systematically analyze existing studies to clarify the neural mechanisms and functional reorganization in Bell's palsy, employing a coordinate-based meta-analysis for more accurate results.
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Background: This study investigated the changes in body composition, muscle contractility and immunocytes of the elderly using three types of walking.

Material And Methods: Seventy-six participants were randomly assigned to control group (CON), slow walking group (SWG), moderate walking group (MWG), or fast walking group (FWG).

Results: Muscle mass in CON decreased (-2.

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Background: Rhythm step training (RST) for sensorimotor dual tasks is in the spotlight as it provides physical activity that is fun and allows participants to express various and creative movements, although it lacks a scientific evidence base. Therefore, this study was to investigate how RST affects the physical and cognitive functions of adolescents. Materials and Methods: A total of sixty-six female middle-schoolers were divided into non-exercise group (control group, CON, n = 22), step training group (STG, n = 22), and rhythm step training group (RSTG, n = 22).

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: Since the start of the COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus II, levels of physical inactivity have become more severe and widespread than ever before. Physical inactivity is known to have a negative effect on the human body, but the extent to which reduced physical fitness has effected immune function before and after the current pandemic has not yet been uncovered. The aim of this study was to investigate the detraining effects of the COVID-19 confinement period on physical fitness, immunocytes, inflammatory cytokines, and proteins in various age groups.

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: Although the plank exercise is difficult to perform for untrained people, it does not require money, special equipment, or much space. However, it is not known how plank exercises affect physical fitness and immunocyte function. This study analyzed the changes in physical fitness and immune cells of a middle-aged man after performing 4 weeks of elbow plank exercise.

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A hindrance to the practical use of sodium-ion batteries is the lack of adequate anode materials. By utilizing the co-intercalation reaction, graphite, which is the most common anode material of lithium-ion batteries, was used for storing sodium ion. However, its performance, such as reversible capacity and coulombic efficiency, remains unsatisfactory for practical needs.

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Trichinella spiralis is a zoonotic nematode and food borne parasite and infection with T. spiralis leads to suppression of the host immune response and other immunopathologies. Alternative activated macrophages (M2) as well as T cells, a target for immunomodulation by the helminth parasite, play a critical role in initiating and modulating the host immune response to parasite.

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Recent studies have attempted to treat autoimmune diseases using Trichuris suis. whipworm) eggs. Large quantities of eggs can be obtained efficiently by collecting from the feces of the porcine hosts rather than by extracting from the female worm uterus.

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Article Synopsis
  • Benign prostatic hyperplasia (BPH) is a common age-related condition affecting 60% of men in their 60s, linked to an imbalance in androgen hormones that disrupts normal cell death and growth.
  • The newly developed formula HBX-5, made from nine medicinal herbs, shows promise in treating BPH by preventing excessive prostate growth and reducing key hormone levels in rats induced with BPH.
  • In vitro studies also indicated that HBX-5 effectively lowered the expression of androgen receptors and related markers in prostate cells, suggesting its potential as a safer alternative to traditional BPH medications.
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Parkinson's disease (PD) is a chronically progressive neurodegenerative disease, with its main pathological hallmarks being a dramatic loss of dopaminergic neurons predominantly in the Substantia Nigra (SN), and the formations of intracytoplasmic Lewy bodies and dystrophic neurites. Alpha-synuclein (α-syn), widely recognized as the most prominent element of the Lewy body, is one of the representative hallmarks in PD. However, the mechanisms behind the increased α-syn expression and aggregation have not yet been clarified.

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Toxascaris leonina galectin (Tl-gal) is a galectin-9 homologue protein isolated from an adult worm of the canine gastrointestinal nematode parasite, and Tl-gal-vaccinated challenge can inhibit inflammation in inflammatory bowel disease-induced mice. We determined the first X-ray structures of full-length Tl-gal complexes with carbohydrates (lactose, N-acetyllactosamine, lacto-N-tetraose, sialyllactose, and glucose). Bonds were formed on concave surfaces of both carbohydrate recognition domains (CRDs) in Tl-gal.

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Background: Acanthamoeba and their proteins can elicit severe allergic airway inflammation in experimental mice.

Objective: Although Acanthamoeba can induce severe allergic airway inflammation in mice, there is no allergenicity data for humans.

Methods: We performed a skin-prick test on 65 patients with chronic cough by using 54 previously known allergens and Acanthamoeba excretory-secretory proteins and enzyme-linked immunosorbent assay on 34 patients to evaluate Acanthamoeba-specific serum immunoglobulin (Ig) levels.

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To determine whether pinworm infections and head lice infestations spread among children in orphanages, 117 children from 4 orphanages in Busan-si and Ulsan-si, Korea, were examined for enterobiasis and head lice infestation between January and February 2014. The overall rate of Enterobius vermicularis egg positivity was 0.85%, whereas none of the children had head lice infestations.

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Objectives: The purpose of this study is to report the clinical effect of Korean medicine (KM) treatment for Henoch-Schonlein purpura (HSP).

Methods: Five HSP patients who demonstrated a Yin deficiency and who had a history of a previous upper respiratory tract infection were included in this study. Four patients had arthritis and three had severe stomachache.

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Objectives: Digital infrared thermographic imaging (DITI) has been used widely for various inflammatory diseases, circulatory diseases, skin diseases, musculoskeletal diseases and cancers. In cases of ligament injury, obviously the temperature of the damaged area increases due to local inflammation; however, whether the temperature also increases due to DITI has not been determined. The purpose of the present study was to identify whether or not the changes of temperature in patient's with medial collateral ligament injury were really due to infrared thermography and to determine the applicability of DITI for assessing ligament injuries.

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Objectives: The purpose of this study was to investigate the current trends in research on pharmacopuncture in Korea since 2007.

Methods: A literature review was performed by using the search engines 'Science and Technology Society Village', 'Korean Studies Information Service System', 'National Discovery for Science Leaders', and 'Oriental Medicine Advanced Searching Integrated System' in Korea from January 2007 to December 2013. Searched key words were 'pharmacopuncture', 'herbal acupuncture', 'aqua-acupuncture', and 'bee venom'.

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Objectives: To investigate the consequences and costs of acupuncture in general medical practice for patients with chronic low back pain (CLBP) in Korea.

Methods: A multicentre observational study was performed. Outpatients with CLBP who received at least one acupuncture session in a Korean Medicine clinic during the study period were included and followed up for 3 months.

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Background: The recruitment of CD4+CD25+Foxp3+T (Treg) cells is one of the most important mechanisms by which parasites down-regulate the immune system.

Methodology/principal Findings: We compared the effects of Treg cells from Trichinella spiralis-infected mice and uninfected mice on experimental allergic airway inflammation in order to understand the functions of parasite-induced Treg cells. After four weeks of T.

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The ascarids, Toxocara canis and Toxascaris leonina, are probably the most common gastrointestinal helminths encountered in dogs. In order to understand biological differences of 2 ascarids, we analyzed gene expression profiles of female adults of T. canis and T.

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Pinworm infection can occur through contact with contaminated surfaces followed by ingestion or even through inhalation of infective eggs. We have limited information regarding environmental contamination by eggs of Enterobius vermicularis. In order to determine environmental risk factors associated with the rate of E.

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In a previous study, we identified an aspartic protease gene (Ts-Asp) from the Trichinella spiralis muscle stage larva cDNA library. The gene sequence of Ts-Asp was 1281 bp long and was found to encode a protein consisting of 405 amino acids, with a molecular mass of 45.248 kD and a pI of 5.

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