Synopsis of recent research by authors named "Sang-Kook Lee"
- Sang-Kook Lee's recent research focuses on the discovery and development of novel anticancer agents, particularly addressing challenges in combating resistant cancer forms such as gemcitabine-resistant pancreatic cancer and various solid tumors.
- Innovative methods including targeted metabologenomics and genomic signature-based screening were employed to discover new bioactive natural products and develop synthetic analogs with promising antiproliferative activities against different cancer cell lines.
- A significant aspect of Lee's work involves elucidating the mechanisms of action of these compounds, demonstrating their potential in regulating key cellular pathways linked to cancer progression, apoptosis, and chemoresistance, thereby contributing to the advancement of cancer therapeutics.
