Publications by authors named "Sang Sook Hong"

Article Synopsis
  • - The study examined the quality and viability of umbilical cord blood (CB) units stored for up to 8 years, focusing on early apoptosis and overall cell health after thawing.
  • - Results showed that CD34+ cells had the highest viability (94.1%) post-thaw, while total nucleated cells (TNCs) had the lowest (78.8%), indicating that different cell types respond differently to long-term storage.
  • - The findings suggest that the viability of CD34+ cells remains consistent with fresh CB, and the rates of necrosis or apoptosis do not increase during storage, which is promising for future transplants using stored CB.
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Emerging resistance to trimethoprim/sulfamethoxazole (SXT) poses a serious threat to the treatment of Stenotrophomonas maltophilia infections. We determined the prevalence and molecular characteristics of acquired SXT resistance in recent clinical S. maltophilia isolates obtained from Korea.

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In this study, we report the first outbreak of KPC-2-producing Klebsiella pneumoniae isolates from three patients admitted to a neurosurgery department in a South Korean teaching hospital. Multilocus sequence typing showed that the isolates were identical to the previous KPC producers in South Korea and other countries, suggesting clonal spread.

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In recent years, there have been increasing reports of KPC-producing Klebsiella pneumoniae in Korea. The modified Hodge test can be used as a phenotypic screening test for class A carbapenamase (CAC)-producing clinical isolates; however, it does not distinguish between carbapenemase types. The confirmation of type of CAC is important to ensure optimal therapy and to prevent transmission.

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