Deciphering risk factors for severe postherpetic neuralgia in patients with herpes zoster: an interpretable machine learning approach.

Introduction: Postherpetic neuralgia (PHN) is a common complication of herpes zoster (HZ). This study aimed to use a large real-world electronic medical records database to determine the optimal machine learning model for predicting the progression to severe PHN and to identify the associated risk factors.

Methods: We analyzed the electronic medical records of 23,326 patients diagnosed with HZ from January 2010 to June 2020.

A low-temperature-tolerant and non-flammable cellulose/HEC/PVA eutectogel for flexible asymmetric supercapacitors.

Asymmetric supercapacitors (ASCs), which combine the advantages of electric double-layer capacitors and pseudocapacitors, have attracted more and more research interest. However, the performance of water-based ASCs often faces the challenge of electrolyte freezing at low temperatures. To resolve the problem, a ternary deep eutectic solvent (DES) with an eutectic point of less than -100 °C was first prepared.

Fireproof Cavity Structure with Enhanced Impact Resistance and Thermal Insulation toward Safeguarding.

Developing devices emphasizing safety protection is becoming increasingly important due to the widespread occurrence of impact damage and thermal hazards. Herein, the F-SSG/TPU-based circular cavity structure (FC) is developed through a convenient and efficient template method, which can effectively achieve anti-impact and thermal insulation for protection. The flame-retardant shear stiffening gel/thermoplastic urethane (F-SSG/TPU) is synthesized through the dynamic interaction between the SSG, TPU, and modified ammonium polyphosphate (APP@UiO-66-NH) by thermo-solvent reactions.

Asymmetric Aramid Aerogel Composite with Durable and Covert Thermal Management via Janus Heat Transfer Structure.

Warmth preservation in cold climates requires a long-term heat supply. Conventional thermal devices usually deliver excessive heat and have difficulty preventing heat loss. Herein, to achieve durable thermal comfort, an asymmetric composite (AAAC) is devised through vacuum-filtrating silver nanowires (AgNWs) onto the surface of a poly(ethylene glycol) (PEG)-infiltrated aramid nanofiber aerogel.

The Effectiveness of Herbal Medicine on Feeding Intolerance in Preterm Infants: A Systematic Review and Meta-Analysis.

Background: Feeding intolerance (FI) refers to frequent feeding disruptions, that can adversely affect the growth, nutritional status, and long-term neurodevelopmental outcomes of preterm infants (born at 37 ≤ weeks of gestation). This review evaluated the efficacy of herbal medicine (HM) for FI compared to conventional treatments.

Methods: An extensive search across 11 databases was conducted, including English, Chinese, and Korean databases, from August 1 to December 7, 2023.

The degree of respiratory depression according to the effect-site concentration in remimazolam target-controlled infusion: A randomised controlled trial.

Background: Remimazolam is not only associated with a lower incidence of respiratory depression than propofol but also in itself has the risk of respiratory depression.

Objective: We investigated respiratory depression following remimazolam infusion, targeting different effect-site concentrations using target-controlled infusion.

Design: A prospective, double-blind, randomised controlled study.

Transcriptome sequencing of the endangered land snail Karaftohelix adamsi from the Island Ulleung: De novo assembly, annotation, valuation of fitness genes and SSR markers.

Background: The Bradybaenidae snail Karaftohelix adamsi is endemic to Korea, with the species tracked from Island Ulleung in North Gyeongsang Province of South Korea. K. adamsi has been classified under the Endangered Wildlife Class II species of Korea and poses a severe risk of extinction following habitat disturbances.

The synergistic effect of herbal medicine and probiotics in pediatric functional constipation: A systematic review and meta-analysis.

Background: Pediatric functional constipation (PFC) is a prevalent and persistent gastrointestinal disorder, that requires various treatments, including alternative approaches. This review assessed the synergistic efficacy of herbal medicine (HM) and probiotics for PFC.

Methods: We conducted a comprehensive search of 11 databases, including English, Chinese, and Korean databases, until June 29, 2023.

Structures and organizations of PSI-AcpPCI supercomplexes from red tidal and coral symbiotic photosynthetic dinoflagellates.

Marine photosynthetic dinoflagellates are a group of successful phytoplankton that can form red tides in the ocean and also symbiosis with corals. These features are closely related to the photosynthetic properties of dinoflagellates. We report here three structures of photosystem I (PSI)-chlorophylls (Chls) /-peridinin protein complex (PSI-AcpPCI) from two species of dinoflagellates by single-particle cryoelectron microscopy.

Structural insights into photosystem II supercomplex and trimeric FCP antennae of a centric diatom Cyclotella meneghiniana.

Diatoms are dominant marine algae and contribute around a quarter of global primary productivity, the success of which is largely attributed to their photosynthetic capacity aided by specific fucoxanthin chlorophyll-binding proteins (FCPs) to enhance the blue-green light absorption under water. We purified a photosystem II (PSII)-FCPII supercomplex and a trimeric FCP from Cyclotella meneghiniana (Cm) and solved their structures by cryo-electron microscopy (cryo-EM). The structures reveal detailed organizations of monomeric, dimeric and trimeric FCP antennae, as well as distinct assemblies of Lhcx6_1 and dimeric FCPII-H in PSII core.

Triple-Responsive Soft Actuator with Plastically Retentive Deformation and Magnetically Programmable Recovery.

Multistimuli responsiveness and programmable shape recovery are crucial for soft actuators in soft robotics, electronics, and wearables. However, existing strategies for actuation cannot attain power-free shape retention after removing the external energy supply. Here, a self-assembled density deposition method was developed to fabricate an electrothermal-NIR-magnetic triple-response actuator which was composed of cellulose nanofiber/poly(vinyl alcohol)/liquid metal (CNF/PVA/LM) and magnetic polydimethylsiloxane (MPDMS) layer.

Size-dependent magnetomechanically enhanced photothermal antibacterial effect of FeO@Au/PDA nanodurian.

The global health crisis of bacterial resistance to antibiotics requires innovative antibacterial strategies. One promising solution is the exploitation of multifunctional nanoplatforms based on non-resistant antibacterial mechanisms. This work reports a novel FeO@Au/polydopamine (PDA) nanodurian with excellent photothermal-magnetomechanic synergistic antibacterial effects.

A MXene@AgAu@PDA nanoplatform loaded with AgAu nanocages for enhancing catalytic activity and antibacterial performance.

With the rapid development of social industrialization, environmental problems seriously threaten people's health, especially water pollution. Therefore, there is an urgent need to construct a multifunctional nanoplatform for different scenarios. Two-dimensional MXene@AgAu@PDA nanosheets loaded with AgAu bimetallic nanocages have been prepared by a one-step method.

Structure of a diatom photosystem II supercomplex containing a member of Lhcx family and dimeric FCPII.

Diatoms rely on fucoxanthin chlorophyll -binding proteins (FCPs) for their great success in oceans, which have a great diversity in their pigment, protein compositions, and subunit organizations. We report a unique structure of photosystem II (PSII)-FCPII supercomplex from at 2.68-Å resolution by cryo-electron microscopy.

Transcriptome analysis of Haemaphysalis flava female using Illumina HiSeq 4000 sequencing: de novo assembly, functional annotation and discovery of SSR markers.

Background: Ticks are ectoparasites capable of directly damaging their hosts and transmitting vector-borne diseases. The ixodid tick Haemaphysalis flava has a broad distribution that extends from East to South Asia. This tick is a reservoir of severe fever with thrombocytopenia syndrome virus (SFTSV) that causes severe hemorrhagic disease, with cases reported from China, Japan and South Korea.

Clinical course of post-kidney transplant Schimke immuno-osseous dysplasia.

Background: Schimke immuno-osseous dysplasia (SIOD) is a rare systemic disease characterized by short stature, proteinuria, and recurrent infections. Patients usually have spondyloepiphyseal dysplasia, and progressive steroid-resistant nephropathy that leads to kidney failure. However, their clinical course after kidney transplantation (KT) is not yet well known.

Structural and functional properties of different types of siphonous LHCII trimers from an intertidal green alga Bryopsis corticulans.

Light-harvesting complexes of photosystem II (LHCIIs) in green algae and plants are vital antenna apparatus for light harvesting, energy transfer, and photoprotection. Here we determined the structure of a siphonous-type LHCII trimer from the intertidal green alga Bryopsis corticulans by X-ray crystallography and cryo-electron microscopy (cryo-EM), and analyzed its functional properties by spectral analysis. The Bryopsis LHCII (Bry-LHCII) structures in both homotrimeric and heterotrimeric form show that green light-absorbing siphonaxanthin and siphonein occupied the sites of lutein and violaxanthin in plant LHCII, and two extra chlorophylls (Chls) b replaced Chls a.

Adsorption of Rhodamine B and Pb(II) from aqueous solution by MoS nanosheet modified biochar: Fabrication, performance, and mechanisms.

Mediated by polydopamine, MoS nanosheets were immobilized on the porous biochar derived from fungus residue, forming a novel biochar-based nanocomposite (MoS-PDA@FRC) for the removal of Rhodamine B(RhB) and Pb(II) from water. Utilizing MoS nanosheets with abundant active adsorption sites, MoS-PDA@FRC showed higher adsorption capacities than raw biochar, with 2.76 and 1.

Wearable Safeguarding Leather Composite with Excellent Sensing, Thermal Management, and Electromagnetic Interference Shielding.

This work illustrates a "soft-toughness" coupling design method to integrate the shear stiffening gel (SSG), natural leather, and nonwoven fabrics (NWF) for preparing leather/MXene/SSG/NWF (LMSN) composite with high anti-impact protecting, piezoresistive sensing, electromagnetic interference (EMI) shielding, and human thermal management performance. Owing to the porous fiber structure of the leather, the MXene nanosheets can penetrate leather to construct a stable 3D conductive network; thus both the LM and LMSN composites exhibit superior conductivity, high Joule heating temperature, and an efficient EMI shielding effectiveness. Due to the excellent energy absorption of the SSG, the LMSN composites possess a huge force-buffering (about 65.

A review of the endangered mollusks transcriptome under the threatened species initiative of Korea.

Transcriptome studies for conservation of endangered mollusks is a proactive approach towards managing threats and uncertainties facing these species in natural environments. The population of these species is declining due to habitat destruction, illicit wildlife trade, and global climate change. These activities risk the free movement of species across the wild landscape, loss of breeding grounds, and restrictions in displaying the physiological attributes so crucial for faunal welfare.

Differential expression of serum mir-363-3p in patients with polycystic ovary syndrome and its predictive value for their pregnancy.

Background: This study aimed to investigate the expression of serum miR-363-3p in patients with polycystic ovary syndrome (PCOS) and its predictive value for pregnancy after ovulation induction therapy.

Methods: The expression of serum miR-363-3p was detected by Reverse transcription quantitative polymerase chain reaction (RT-qPCR). PCOS patients were treated with ovulation induction therapy, and after the successful pregnancy was confirmed, they were followed up for 1 year in outpatient department to record the pregnancy outcomes of the patients.

Individual phosphatidylinositol transfer proteins have distinct functions that do not involve lipid transfer activity.

Platelets use signal transduction pathways facilitated by class I phosphatidylinositol transfer proteins (PITPs). The 2 mammalian class I PITPs, PITPα and PITPβ, are single PITP domain soluble proteins that are encoded by different genes and share 77% sequence identity, although their individual roles in mammalian biology remain uncharacterized. These proteins are believed to shuttle phosphatidylinositol and phosphatidylcholine between separate intracellular membrane compartments, thereby regulating phosphoinositide synthesis and second messenger formation.

Transcriptome analysis of the endangered dung beetle Copris tripartitus (Coleoptera: Scarabaeidae) and characterization of genes associated to immunity, growth, and reproduction.

Background: Dung beetles recycle organic matter through the decomposition of feces and support ecological balance. However, these insects are threatened by the indiscriminate use of agrochemicals and habitat destruction. Copris tripartitus Waterhouse (Coleoptera: Scarabaeidae), a dung beetle, is listed as a class-II Korean endangered species.

Ultra-Stretchable Spiral Hybrid Conductive Fiber with 500%-Strain Electric Stability and Deformation-Independent Linear Temperature Response.

Stretchable configuration occupies priority in devising flexible conductors used in intelligent electronics and implantable sensors. While most conductive configurations cannot suppress electrical variations against extreme deformation and ignore inherent material characteristics. Herein, a spiral hybrid conductive fiber (SHCF) composed of aramid polymeric matrix and silver nanowires (AgNWs) coating is fabricated through shaping and dipping processes.