Primary intraocular (retinal) lymphoma after ocular toxoplasmosis.

Purpose: Toxoplasmosis gondii is a common worldwide parasite that presents in the eye with focal retinochoriditis and vitritis. Although it is rare, ocular toxoplasmosis has been linked to primary intraocular (retinal) lymphoma, which is mostly a diffuse large B-cell lymphoma.

Methods: An elderly female patient was treated for recurrent ocular toxoplasmosis, and because of progressive vitritis, a diagnostic vitrectomy was performed.

Longitudinal study of new eye lesions in children with toxoplasmosis who were not treated during the first year of life.

Purpose: To determine the incidence of new chorioretinal lesions in children with toxoplasmosis diagnosed after, and therefore not treated during, their first year.

Design: Prospective longitudinal cohort study.

Methods: Thirty-eight children were evaluated in Chicago between 1981 and 2005 for new chorioretinal lesions.

Longitudinal study of new eye lesions in treated congenital toxoplasmosis.

Objective: To determine the incidence of new chorioretinal lesions in patients with congenital toxoplasmosis who were treated throughout their first year of life.

Design: Prospective longitudinal observation of a cohort.

Participants: One hundred thirty-two children were studied as part of the longitudinal observation.

A model of spectral filtering to reduce photochemical damage in age-related macular degeneration.

Background/purpose: Cumulative sunlight exposure and cataract surgery are reported risk factors for advanced age-related macular degeneration (AMD). Laboratory studies suggest that accumulation and photochemical reactions of A2E (N-retinylidene-N-retinylethanolamine) and its epoxides, components of lipofuscin, are important in AMD. To relate this data to the clinical setting, we modeled the effects of macular irradiance and spectral filtering on production of A2E and reactive oxygen intermediates (ROIs) in pseudophakic eyes with a clear or "yellow" intraocular lens (IOL) and in phakic eyes.

Recurrent retinal detachment more than 1 year after reattachment.

Purpose: Little information exists regarding recurrent retinal detachment after 1 or more years of complete retinal reattachment. To better understand this uncommon problem, we evaluated late recurrent retinal detachments in relation to the contemporary classification of proliferative vitreoretinopathy (PVR).

Design: Retrospective consecutive noncomparative case series.