Publications by authors named "Sandy M Reid"
Article Synopsis
- Expanding cellular therapies for cancer has been difficult due to a lack of specific surface markers, prompting researchers to explore new methods for identifying these markers.
- The study introduces a novel approach called 'structural surfaceomics', using cross-linking mass spectrometry to discover unique protein conformations on tumor cells that standard methods might miss.
- Applying this technique to acute myeloid leukemia (AML), researchers identified a specific target, developed antibodies, and demonstrated that chimeric antigen receptor T cells can effectively eliminate AML cells while sparing normal cells, showing potential for broader applications in cancer therapy.
