Publications by authors named "Sandy J Falk"

As the majority of female cancer survivors can now expect to live long lives beyond cancer diagnosis and treatment, there is a growing need to address the significant late effects of treatment. Unfortunately, sexual health remains a primary concern that often goes unaddressed among female cancer survivors. Sexual dysfunction is one of the most common and distressing effects of treatment.

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Cancer and Female Sexual Function.

Obstet Gynecol Clin North Am

June 2024

Sexual health is a concern that often goes unaddressed among female cancer survivors. Management of these issues depends upon the type of malignancy, stage and other tumor characteristics, treatment, and the history, concerns, and goals of the individual patient.

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Chronic graft-versus-host disease is a major complication of allogeneic hematopoietic cell transplantation and a leading cause of long-term morbidity, nonrelapse mortality, and impaired health-related quality of life. The skin is commonly affected and presents heterogeneously, making the role of dermatologists critical in both diagnosis and treatment. In addition, new clinical classification and grading schemes inform treatment algorithms, which now include 3 U.

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Article Synopsis
  • Chronic graft-versus-host disease (cGVHD) is a common and serious complication after allogeneic stem cell transplants, leading to long-term health issues and decreased quality of life.
  • The skin is frequently impacted by cGVHD, necessitating dermatologists' expertise for accurate diagnosis and effective treatment.
  • Recent advances include new classification systems, therapeutic options approved by the FDA, and evolving transplant methods that are reshaping our understanding of cGVHD.
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Objective: To review the sexual health issues cancer survivors may experience, including incidence, association with treatment modalities, and approach to evaluation and treatment.

Data Sources: Peer-reviewed journal articles, medical society or government Web sites.

Conclusion: Cancer diagnosis and treatment often impacts sexual function and addressing this is a key component of health-related quality of life.

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There are increasing numbers of breast cancer survivors. Chemotherapy or endocrine therapy result in effects on vaginal health that may affect quality of life. These effects may impact sexual function, daily comfort, or the ability to perform a pelvic examination.

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Purpose Of Review: Young women (<45 years of age) diagnosed with breast cancer face increased risk of sexual dysfunction as a result of their cancer-directed treatment. We will review the recent literature examining this critical challenge and discuss current efforts to address sexual dysfunction.

Recent Findings: In the period since 2013, the literature has focused on sexual issues that result from the premature onset of menopausal symptoms and changes in sexual health following breast surgery.

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Approximately 14 million people have a history of cancer in the United States alone, and the number is expected to increase with time. This has prompted an appreciation of the quality of life for survivors. Women treated for cancer identify gynecologic issues as a major concern for both general health and the negative impact on sexual function that follow the cancer diagnosis and subsequent treatment.

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Article Synopsis
  • The study aimed to analyze maternal and neonatal outcomes in expectant management of spontaneous preterm premature rupture of membranes (PPROM) before 24 weeks of pregnancy.
  • A total of 108 pregnancies were assessed, with 57 opting for expectant management, revealing a median latency from membrane rupture to delivery of 6 days and an overall neonatal survival rate of 26.3%.
  • Results showed that while survival rates improved slightly with gestational age at the time of rupture, survival before 20 weeks was notably low and complications like chorioamnionitis occurred in nearly a third of cases, with no maternal fatalities reported.
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