Publications by authors named "Sandrine Venier"
Cardiac implantable electronic devices and their integrated thoracic impedance sensors have been used to detect sleep apnea for over a decade now. Despite their usage in daily clinical practice, there are only limited data on their diagnostic accuracy. AIRLESS and UPGRADE were prospective investigator-driven trials meant to validate the AP scan (Boston Scientific, Marlborough, MA, USA) in heart failure cohorts.
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- Pulsed field ablation (PFA) is gaining popularity as a treatment for atrial fibrillation, but its impact on hemolysis (destruction of red blood cells) has not been thoroughly studied.
- In this study involving 145 patients receiving PFA and 70 patients undergoing radiofrequency ablation, significant hemolysis was found predominantly in the PFA group, with 94.3% affected compared to just 6.8% in the radiofrequency group.
- Higher numbers of PFA deliveries correlated with increased hemolysis severity, with notable increases in biomarkers indicating red blood cell damage and renal function impacts, especially in patients with lower baseline kidney function.
Article Synopsis
- PFA (Pulsed Field Ablation) is being explored as a new treatment for atrial fibrillation but has been linked to cases of acute kidney injury due to haemolysis.
- A study involved 68 patients; about 28% showed significant haemolysis indicated by depleted haptoglobin levels, with higher application numbers correlating to increased risk.
- While acute kidney injury is rare after PFA, it's important to monitor the number of applications to prevent severe haemolysis.
Article Synopsis
- Catheter ablation outcomes for non-paroxysmal atrial fibrillation (AF) are generally unsatisfactory, and using a non-invasive method to assess atrial cardiomyopathy (ACM) in patients could help identify those who would respond best to treatment.
- In a study of 295 patients who underwent cryoballoon-PVI, researchers measured the duration of amplified P-wave (APW) and found that those with a longer APW (≥150 ms) had a significantly higher recurrence rate of arrhythmia post-ablation compared to those with shorter APW (<150 ms).
- The study concluded that measuring APW is a simple, non-invasive way to predict which patients are more likely to have worse outcomes after PVI
Recurrences of Atrial Fibrillation Despite Durable Pulmonary Vein Isolation: The PARTY-PVI Study.
Circ Arrhythm Electrophysiol
March 2023
Background: Recurrences of atrial fibrillation (AF) after pulmonary vein isolation (PVI) are mainly due to pulmonary vein reconnection. However, a growing number of patients have AF recurrences despite durable PVI. The optimal ablative strategy for these patients is unknown.
View Article and Find Full Text PDFAims: The aim of this study was to compare procedural efficacy and safety, including 1-year freedom from AF recurrence, between the novel cryoballoon system PolarX (Boston Scientific) and the Arctic Front Advance Pro (AFA-Pro) (Medtronic), in patients with paroxysmal AF undergoing PVI.
Methods And Results: This multicentre prospective observational study included 267 consecutive patients undergoing a first cryoablation procedure for paroxysmal AF (137 PolarX, 130 AFA-Pro). Kaplan-Meier curves with the log-rank test was used to compare the 1-year freedom from AF recurrence between both groups.
Article Synopsis
- The study focused on understanding the factors that lead to inappropriate shocks from subcutaneous implantable cardioverter defibrillators (S-ICDs) in patients.
- The research involved 300 patients over an average follow-up of about 23 months, finding that 8.7% experienced inappropriate shocks primarily due to supraventricular arrhythmias and sensing issues.
- Key factors identified that predicted the risk of inappropriate shocks included fewer sensing vectors during pre-implant screening, specific ECG characteristics, a history of certain heart conditions, and being overweight.
Background: Radiofrequency catheter ablation is considered to be a relatively safe procedure. This is an unusual case report in which severe mitral regurgitation was occurred after left lateral accessory pathway radiofrequency catheter ablation.
Case Presentation: A 15-year-old man without structural heart disease was referred for ablation of a left lateral accessory pathway.
Aims: Despite advances in interventional treatment strategies, atrial fibrillation (AF) remains associated with significant morbidity and mortality. Fibrotic atrial myopathy (FAM) is a main factor for adverse outcomes of AF-ablation, but complex to diagnose using current methods. We aimed to derive a scoring system based entirely on easily available clinical parameters to predict FAM and ablation-success in everyday care.
View Article and Find Full Text PDFAims: Totally leadless cardiac resynchronization therapy (CRT) can be delivered with a combination of Micra and WiSE-CRT systems. We describe the technical feasibility and first insights into the safety and efficacy of this combination in European experience.
Methods And Results: Patients enrolled had indication for both Micra and WiSE-CRT systems because of heart failure related to high burden of pacing by a Micra necessitating system upgrade or inability to implant a conventional CRT system because of infectious or anatomical conditions.
Diagnosis of sleep apnea (SA) using simple tools has the potential to improve the efficacy of cardiac implants in the prevention of cardiac arrhythmias. The aim of the present study was to validate a transthoracic impedance sensor for SA diagnosis in patients with cardiac implants. We compared the apnea-hypopnea index (AHI) obtained from polysomnography (AHI) with the AHI obtained from autoscoring algorithms of the ApneaScan implantable impedance respiration sensor (AHI) three months after implantation of cardioverter-defibrillator (ICD) or cardiac resynchronization therapy-defibrillator (CRT-D) devices.
View Article and Find Full Text PDFBackground: Transcatheter left atrial appendage (LAA) occlusion is an alternative strategy for stroke prevention in patients with atrial fibrillation (AF).
Objectives: This study sought to determine the incidence, predictors, and prognosis of thrombus formation on devices in patients with AF who were treated with LAA closure.
Methods: The study retrospectively analyzed data from patients treated with 2 LAA closure devices seen in 8 centers in France from February 2012 to January 2017.
Aims: It remains unknown whether contact force (CF) sensing technology is of value for cavotricuspid isthmus (CTI) ablation. We prospectively evaluated procedural parameters and outcomes of CF-guided vs. CF-blinded CTI ablation for typical atrial flutter (AFL).
View Article and Find Full Text PDFBackground: Fluoroscopic guidance is used to position catheters during cardiac ablation. We evaluated the impact of a novel nonfluoroscopic sensor-guided electromagnetic navigation system (MG) on radiation exposure during catheter ablation of atrial fibrillation (AF) or atrial flutter (AFL).
Methods: A total of 134 consecutive patients referred for ablation of AF (n = 44) or AFL (n = 90) ablation were prospectively enrolled.