Relationship between apo(a) length polymorphism and lipoprotein(a) concentration in healthy Ivorian subjects with single or double apo(a) isoforms.

Objectives: To determine the relationship between apo(a) size and Lp(a) concentration in healthy Ivorian subjects.

Methods: Serum Lp(a) was measured by immunonephelometry and electroimmunodiffusion, and apo(a) size determined by immunoblotting.

Results: Both assay methods provided comparable information.

A different approach to analyzing age-related HbA1c values in non-diabetic subjects.

Using appropriate statistical tests and taking into account the analytical performance of hemoglobin A1c (HbA1c) measurements, is it useful to establish HbA1c age-related values in non-diabetic subjects? Non-diabetic subjects (n=135, 72 women and 63 men) from the neuromuscular department of the Pitié-Salpétrière Hospital (Paris) were involved in our study. Subjects were divided into two groups related to age: 51 patients under 50 years old and 84 subjects aged 50 years or more. Fasting plasma glucose and HbA1c measurements were respectively performed by enzymatic assay using the hexokinase method and high-performance liquid chromatography based on the ion exchange methodology with high precision.