Publications by authors named "Sandrine Soriot-Thomas"
Article Synopsis
- Non-steroidal anti-inflammatory drugs (NSAIDs) are often used for managing acute postoperative pain after surgery, but their use in cardiac procedures raises concerns about risks like increased bleeding and kidney injury.
- The KETOPAIN trial aims to evaluate the effectiveness and safety of ketoprofen in treating postoperative pain in cardiac surgery patients, involving 238 participants randomized to receive either ketoprofen or a placebo after the procedure.
- The study will assess various outcomes, including pain intensity at 24 hours post-surgery, opioid consumption, complications, and quality of life up to three months afterward.
Background: Chronic pain affects approximately 30% of the general population, severely degrades quality of life and professional life, and leads to additional health care costs. Moreover, the medical follow-up of patients with chronic pain remains complex and provides only fragmentary data on painful daily experiences. This situation makes the management of patients with chronic pain less than optimal and may partly explain the lack of effectiveness of current therapies.
View Article and Find Full Text PDFIntroduction: In France, the number of hospitals involved in clinical research and committed to a quality approach is increasing. The objective of such approaches is to ensure the safety of patients involved in research projects by improving quality.
Objective: The University Hospital of Amiens has chosen to certify all its clinical research activities in the same scope according to the ISO 9001: 2015 standard.
Introduction: Despite their poor tolerance, especially in the elderly, weak opioids (WO) remain commonly prescribed for patients with knee osteoarthritis (KOA). We compared the efficacy and safety of a new wearable transcutaneous electrical nerve stimulation (W-TENS) device with WO for the treatment of moderate-to-severe, nociceptive KOA chronic pain.
Methods: The study was a non-inferiority, multicentric, prospective, randomized, single-blind, controlled, 2-parallel groups Trial.
Background: Data on microcirculatory pattern of COVID-19 critically ill patients are scarce. The objective was to compare sublingual microcirculation parameters of critically ill patients according to the severity of the disease.
Methods: The study is a single-center prospective study with critically ill COVID-19 patients admitted in ICU.