Effect of repetitive arm cycling following botulinum toxin injection for poststroke spasticity: evidence from FMRI.

Background And Objective: Investigations were performed to establish if repetitive arm cycling training enhances the antispastic effect of intramuscular botulinum toxin (BTX) injections in postischemic spastic hemiparesis. Effects on cerebral activation were evaluated by functional magnetic resonance imaging (fMRI).

Methods: Eight chronic spastic hemisyndrome patients (49 ± 10 years) after middle cerebral artery infarction (5.