Alpha1-antitrypsin gene polymorphisms are not associated with renal arterial fibromuscular dysplasia.

Objective: We previously showed that fibromuscular dysplasia (FMD) of the renal artery may be familial. Case reports have associated alpha1-antitrypsin deficiency and FMD. The aim of this study was to test the implication of the alpha1-antitrypsin (AAT) gene in a large cohort of patients with renal FMD.