Evaluation of right and left ventricular function in patients with ischemic heart disease complicated by mitral insufficiency.

Aim      To evaluate the right and left ventricular function and their interaction in patients with ischemic heart disease (IHD) complicated with mitral valve insufficiency (MVI) according to data of echocardiography (EchoCG) with the strain in gray scale, vector and diagram analyses.Material and methods  The study included 118 patients evaluated with EchoCG at the preoperative stage of treatment; 71 of these patients had ischemic MVI (group 1) and 47 patients had uncomplicated IHD (group 2 or comparison group). Mean age of patients was 64±10 years.

[Intraventricular blood flows and myocardial contractility in impairments of coronary circulation].

We examined a total of 106 patients with ischaemic heart disease (mean age - 59±7 years) and 30 apparently healthy people (mean age - 36±4 years). Myocardial revascularization was performed with the help of stenting and coronary artery bypass grafting. The patients with ischaemic heart disease were divided into 2 groups: Group 1 with postinfarction cardiosclerosis and Group 2 without Q-forming myocardial infarction.

[Echocardiography in the Assessment of Intraventricular Flows and Pressure Gradients in Obstructive Hypertrophic Cardiomyopathy].

Aim      To evaluate results of myomectomy by intraventricular pressure gradients (IVPG) and blood flows in patients with obstructive hypertrophic cardiomyopathy (OHCMP).Material and methods  The study included a total of 76 subjects, 42 patients with OHCMP (mean age, 39±7 years) and 34 healthy volunteers (mean age, 41±3 years). Prior to and after myomectomy, transthoracic echocardiography was performed and followed by digital image processing and calculation of IVPG and left ventricular (LV) vortex flows.

[New Algorithms for Evaluation Myocardial Function According to Echocardiography].

The article is devoted to the novel methodological approach to assessment of function of the myocardium and the left ventricle as a whole with the help of modern methods of processing ultrasound images obtained by echocardiography. It contains presentation of theoretical prerequisites for elaboration of a new direction, as well as mathematical computations basing on which quantitative parameters for assessment of myocardial function and blood flows within chambers of the heart were obtained. The fundamental principle in assessing these parameters was the use of the phase structure of the cardiac cycle.

[Vector mapping of deformation and blood flows in patients with ascending aortic aneurysm].

The authors performed clinical studies based on modelling of an ascending aortic aneurysm in 37 patients and 10 apparently healthy subjects. Echocardiography was carried out in the B-mode using the Vivid E9 device (USA, GE). The linear dimensions of the aorta were assessed at three points - in the immediate vicinity of the valves, in the area of the maximum dilatation and in the area of decreased dilatation with registration of blood flow velocity in the aorta.

[Phenomenological Regularities of Assessment of Left Ventricle Function in Mitral Valve Insufficiency].

Objective: to examine relationship between anatomical changes of the left ventricle (LV), dynamics of velocity of its volume modification, and blood flows in the LV in patients with mitral regurgitation (MR) before and after surgical treatment.

Materials And Methods: We included into this study 58 patients with severe 3-4 degree MR (38 men, 20 women aged 24-69 [mean age 51±9] years) in sinus rhythm (96 %) or atrial fibrillation (4 %). The control group included 86 healthy volunteers, mean age 39±7 years.

Transesophageal vs. intracardiac echocardiographic screening in patients undergoing atrial fibrillation ablation with uninterrupted rivaroxaban.

Background: Patients with atrial fibrillation (AF) routinely undergo different imaging modalities for the evaluation of the left atrial (LA) appendage to rule out thrombus prior to the AF ablation procedure. Recently, uninterrupted novel oral anticoagulants were introduced for patients undergoing atrial fibrillation (AF) ablation to minimize the peri-procedural thromboembolism risk. We performed a retrospective analysis to evaluate the safety of uninterrupted rivaroxaban and whether transesophageal (TEE) or intracardiac echocardiography (ICE) is necessary for patients undergoing AF ablation.

[ASSESSMENT OF LIVER FUNCTION WITH TRANSESOPHAGEAL ECHOCARDIOGRAPHY HEART SURGERY WITH CARDIOPULMONARY BYPASS].

Aim Of The Study: evaluation of arterial and venous liver circulation during cardiopulmonary bypass (CPB) using the method of transesophageal echocardiography (TEE).

Materials And Methods: 62 patients undergoing reconstructive cardiac surgery with CPB were analyzed. During all the stages of treatment we performed monitoring of mean arterial pressure, heart rate and central venous pressure.

[PREDICTORS OF RISK OF SURGERIES IN PATIENTS WITH FAILURE OF THE CORONARY CIRCULATION].

The paper analyzes the study of the myocardium in patients with coronary artery disease to identify new predictors of reduction of myocardial contractility. Research carried out on the basis of transthoracic echocardiography and transesophageal on Vivid 7 unit and Vivid-E9 with multifrequency array sensor (3.5-5.

[Infective Endocarditis: Problems of Diagnosis and Treatment].

Results of the clinical study involving 458 patients (from 12 to 75 years, mean age 49 +/- 9.3 years) with various forms of infective endocarditis (IE) have been summarized. Integrated echocardiography was the principal non-invasive method of presurgical diagnosis of the disease.

[Respiratory support in anaesthetic management for thoracic surgery and their comparative characteristics: over 2000 anaesthesia experience].

The article deals with the first comparative study of haemodynamics, gas exchange, and metabolic lung finction in patients with underlying respiratory and cardiovascular diseases. Different anaesthesia and ventilation (conventional AVL, OLV differentiated ALV) techniques were used. Respiratory support methodology with the use of HFV or CPAP during the main phase of thoracic surgery in patients with severe associated cardio-respiratory diseases was developed.

[Noninvasive registration of turbulent flows in the left ventricle].

Observation results of 133 patients with chronic heart insufficiency and 29 healthy people, all aged 41 ± 6 years were analyzed. 51 patients had ischemic heart disease, 53 had various valvular diseases and 30 patients had dilated cardiomyopathy. Echocardiography was performed together with ECG.

Alemtuzumab induction in pediatric kidney transplantation.

Recipient parenchymal lymphatic cells are crucial for direct and indirect pathways of allorecognition. We proposed that alemtuzumab, being infused several weeks pretransplant could eradicate peripheral lymphatic cells and promote donor-specific tolerance. We present here a single center, retrospective review of 101 consecutive living-donor kidney transplantations to pediatric patients aged from seven month to 18 yr, performed between September 2006 and April 2010.

[Assessment of velocity of deformation of abdominal aorta wall with the help of the multivox working station].

Most frequent cause of abnormalities of elastic properties of walls of abdominal aorta is development of atherosclerosis resulting in replacement of elastin by simpler fibrillar proteins and collagen. This subsequently leads to dilation of the aorta and formation of aneurism. Increase of collagen content in the aortic wall correlates with growth of aneurism dimensions.

[Surgical treatment of rectocele with the use of mesh implants by the obstructive defecation syndrome].

Unlabelled: The aim of current study was to evaluate in complex the effectiveness of transvaginal mesh implants in women with obstructed defecation (OD) syndrome based on the comparison of preoperative and postoperative results of objective diagnostic tools and quality of life parameters.

Methods: from prospectively collected database of patients treated in our department those who were treated for OD by means of transvaginally placed mesh implants were chosen. The comparison of pre- and postoperative results of objective evaluation (prolapse stage according to POP-Q system, X-ray defecography - XR-DG and MRI defecography - MRI-DG) as well quality of life parameters (Wexner constipation score and validated Russian version of King's Health Questionnaire) was undertaken.

[Carotid endarterectomy or carotid stenting: optimal therapeutic decision-making for patients with carotid artery stenoses].

The work was aimed at comparatively studying the outcomes of carotid endarterectomy and carotid stenting for optimal therapeutic decision-making in patients presenting with carotid artery stenoses. We examined and treated a total of one hundred and sixty-seven patients. In the group of endarterectomy, we performed a total of 91 operations in 85 patients, and in the group of carotid stenting, a total of 87 stenting procedures were carried out on the internal carotid artery with cerebral protection in 82 patients.

[Effect of propofol-based combined anesthesia on the development of adaptive mechanisms to the prolonged one-lung artificial ventilation].

The paper deals with the assessment of the adequacy and safety of multicomponent anesthesia based on propofol at lung surgery requiring one-lung ventilation (OLV) in patients with chronic respiratory diseases and with the evaluation of the effect of propofol on the development of adaptive mechanisms in various ventilation modalities in thoracic surgery. The pressor, resistive, and volume characteristics of pulmonary blood flow, systemic and intracardiac hemodynamics under artificial ventilation (AV) and OLV of a duration of up to 1.5 hours by a combination of pulmonal and transpulmonal thermodilution on a PiCCO plus device with a VOLEF attachment were compared.

[Hemodynamic monitoring from the data of intracardiac and transesophageal echocardiography].

The constantly increasing complexity and duration of surgical intervention, comorbidity that leads to severe circulatory and respiratory disorders, multifactoriness of functional and metabolic disorders--this also needs a rapid and accurate assessment of patients and objective monitoring. The value of monitoring is determined by the results of timely diagnosis of disorders and the prevention of severe complications, including circulatory arrest, regional and global systolic function of the ventricles, which undoubtedly assists in choosing the tactic of intensive care. Intracardiac echocardiography makes it possible to record changes in cardiac cavity volume in real time, to calculate ejection fraction as the major pump coefficient, which is of prime importance in the surgical correction of coronary circulation with one-stage correction of mitral insufficiency.

[Surgical decision-making in management of patients with lower limb critical ischaemia using radioisotope scintigraphy].

Presented herein is a new technique of studying the competence of the microcirculatory bed and viability of appendicular tissues in patients suffering from lower limb critical ischaemia. The competence of the resistive link of microcirculation was determined by means of dynamic scintigraphy based on studying the primary passage of an internally administered radiopharmaceutical along the microcirculatory system. Accumulation of the radiopharmaceutical with an affinity for the sites of necrosis and inflammation was recorded by means of stationary scintigraphy.

[Use of loading test to predict intraoperative heart failure in cardiosurgical patients].

The paper deals with the development of a procedure for using loading tests to predict the development of intraoperative heart failure in cardiosurgical patients. A volumetric loading test (limb elevation) was carried out to assess the mechanisms of responsible for the regulation of performance of the heart and the efficiency of its work. Cardiac output, end diastolic volume index, and ejection fraction were recorded and a hemodynamic response was assessed from their changes.

[Myocardial biomechanics in patients with coronary circulatory insufficiency].

The paper analyzes a new approach to evaluating myocardial systolic and diastolic function, which is based on recording of the rate of myocardial displacement in different phases of a cardiac cycle. Changes in the rate of vector movements in a period of isovolumic contraction and relaxation are shown on ample clinical materials in both healthy individuals and patients with coronary heart disease. There is evidence for a significant difference in the performance of a stress test by healthy individuals and patients with a low coronary circulatory reserve.

[Ultrasound transcranial monitoring during aortocoronary bypass surgery under extracorporeal circulation].

The paper deals with the assessment of hemodynamic parameters in the region of the circle of Willis, by using various exercise tests and transcranial Doppler study during cardiac operations under extracorporeal circulation. Some points of the timely diagnosis of air and material microembolisms are specified. There is evidence that the application of these procedures is substantiated and they may be employed in clinical practice to undertake earlier preventive measures against cervical circulatory disorders.