Publications by authors named "Sandra Vyssoki"

Background: Prevalence of cognitive decline and dementia is rising globally, with more than 10 million new cases every year. These conditions cause a significant burden for individuals, their caregivers, and health care systems. As no causal treatment for dementia exists, prevention of cognitive decline is of utmost importance.

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  • The study investigates the presence of a seasonal pattern in major depressive disorder (MDD) across a 14-year period in Austria, revealing a significant variation in hospitalization rates based on the seasons.
  • Results showed that both men and women had fewer admissions during summer and December for moderate to severe MDD, while women specifically exhibited a seasonal pattern for psychotic depression.
  • It also found that patients over 55 experienced a reduced seasonal pattern, suggesting that age influences the severity of MDD symptoms associated with seasonal changes.
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Background: Older adults exhibit heightened vulnerability for alcohol-related health impairments. Increases in the proportion of older adults within the European Union's total population and prevalence rates of alcohol use disorders in this age group are being observed. This large scale international study was conducted to identify those older adults with an increased risk to engage in hazardous drinking behaviour.

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  • Alcohol use disorder (AUD) is prevalent and heavily burdens health systems worldwide, with end-stage alcohol-related liver disease (ARLD) being the most severe outcome requiring liver transplantation (LTX) for a cure.
  • This study reviews various epidemiological models estimating the prevalence of AUD and ARLD while recalculating these estimates using the latest data from Austria and comparing them to LTX statistics.
  • The findings indicate that AUD prevalence might be underestimated, with rates ranging from 4.1% to 10.1% among those over 15 years, and a significant gap between ARLD deaths and available LTXs, highlighting regional disparities in organ supply.
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The potentially deleterious and teratogen effects of alcohol consumption during pregnancy are an important medical as well as socio-economic topic. Maintaining the necessary strict abstinence is especially challenging for pregnant women diagnosed with alcohol dependence. Due to limited data, optimal pharmacological treatment is seldom possible.

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Background: The prevalence of major depressive disorder (MDD) in women is up to 50% higher as compared to men. However, little is known about discrepancies in health care utilization between depressed female and male patients. Consequently, the aim of the present study was to elucidate gender differences regarding the frequency of hospital admissions and the length of inpatient treatment for MDD across the lifespan.

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Aims: Alcohol is an important risk factor for morbidity and mortality, especially within the European region. Differences in per capita consumption and drinking patterns are possible reasons for regional differences and diverging trends in alcohol-related health outcomes.

Methods: Twenty-nine countries within the World Health Organization (WHO) European region were evaluated for trends and predictions in alcohol-related deaths within the last four decades using data available from the WHO Health for All database.

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Aims: Patients with alcohol use disorder (AUD) frequently suffer from cognitive deficits ranging from mild symptoms to most severe forms. Wernicke encephalopathy (WE), caused by thiamine deficiency, is a potentially fatal syndrome characterized by the clinical triad of ophthalmoplegia, ataxia, and confusion. WE frequently presents in patients with AUD and, if left untreated, can progress to Wernicke-Korsakoff syndrome, which constitutes severe anterograde amnesia, confabulation, and behavioral abnormalities.

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Background: Mood episodes in bipolar disorder (BD) are reported to exhibit a seasonal pattern (SP). However, it is unclear whether this pattern is influenced by a patient's sex and age.

Methods: In this nationwide registry study, we examined all inpatient treatments due to a manic (F31.

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