Publications by authors named "Sandra Vohrnova"
Unlabelled: The paper presents the study of a set of isolates of , which comprised two heterogeneous subpopulations, one of which was susceptible and the other resistant to optochin. The aim of the study was to compare the results of serotyping, multilocus sequence typing (MLST), ribosomal multilocus sequence typing (rMLST), and variation analysis of these subpopulations and to investigate the genetic probable causes of optochin resistance. The strains studied were cultured from samples taken from patients with invasive pneumococcal disease in the Czech Republic in 2019 and 2020.
View Article and Find Full Text PDFMicrobiology reference laboratories perform a crucial role within public health systems. This role was especially evident during the COVID-19 pandemic. In this Viewpoint, we emphasise the importance of microbiology reference laboratories and highlight the types of digital data and expertise they provide, which benefit national and international public health.
View Article and Find Full Text PDFArticle Synopsis
- The IRIS Consortium investigated the impact of the COVID-19 pandemic on invasive diseases caused by specific bacteria over a four-year period, comparing data from before and during the pandemic.
- Laboratories from 30 countries provided surveillance data, revealing a significant decrease in cases of Streptococcus pneumoniae, Haemophilus influenzae, and Neisseria meningitidis during the pandemic, while Streptococcus agalactiae cases remained unchanged.
- An estimated 36,289 cases of invasive bacterial disease were prevented due to COVID-19 containment measures during the first two years of the pandemic.
Changes in the incidence of invasive disease due to Streptococcus pneumoniae, Haemophilus influenzae, and Neisseria meningitidis during the COVID-19 pandemic in 26 countries and territories in the Invasive Respiratory Infection Surveillance Initiative: a prospective analysis of surveillance data.
Lancet Digit Health
June 2021
Background: Streptococcus pneumoniae, Haemophilus influenzae, and Neisseria meningitidis, which are typically transmitted via respiratory droplets, are leading causes of invasive diseases, including bacteraemic pneumonia and meningitis, and of secondary infections subsequent to post-viral respiratory disease. The aim of this study was to investigate the incidence of invasive disease due to these pathogens during the early months of the COVID-19 pandemic.
Methods: In this prospective analysis of surveillance data, laboratories in 26 countries and territories across six continents submitted data on cases of invasive disease due to S pneumoniae, H influenzae, and N meningitidis from Jan 1, 2018, to May, 31, 2020, as part of the Invasive Respiratory Infection Surveillance (IRIS) Initiative.