Publications by authors named "Sandra Terroba-Seara"
Pulmonary artery peak Doppler velocity as an estimator of systemic blood flow and predictor of intraventricular haemorrhage in preterm infants: a multicentre prognostic accuracy study.
Arch Dis Child Fetal Neonatal Ed
December 2024
Objectives: (1) To assess how main pulmonary artery peak Doppler velocity (MPAVpeak) correlates with right ventricular output (RVO) and superior vena cava flow (SVCf), (2) to assess the reproducibility of MPAVpeak and (3) to test the prognostic accuracy of MPAVpeak to predict high-grade intraventricular haemorrhage (IVH) or death at seventh day of life.
Design: Prospective cohort study.
Setting: Nine third-level neonatal units in Spain.
Article Synopsis
- The study aimed to see if early echocardiography screening in preterm infants with low systemic blood flow can lower the risk of intraventricular hemorrhage (IVH) and death.
- Conducted across nine neonatal units, infants under 33 weeks gestation were split into two groups: one receiving early screening and the other not.
- Results showed that early screening significantly decreased the chances of developing severe IVH or dying in the first week of life.
Objective: This study aimed to assess whether bedside ultrasound (BUS) as the first imaging modality allows an earlier diagnosis of necrotizing enterocolitis (NEC) compared with abdominal radiography.
Study Design: A before-after controlled study in preterm infants with suspected NEC. The intervention group (October 2019-October 2021) received BUS as the first imaging modality and was managed accordingly to BUS findings.
Article Synopsis
- COVID-19, originating in Wuhan in late 2019, has been linked to severe cardiovascular complications, particularly coagulopathy, which is a life-threatening issue that increases mortality but lacks clear prevention or treatment guidelines.
- A case of a 70-year-old woman illustrates the severe effects of COVID-19 as she developed extensive coagulopathy leading to multiple embolisms and ultimately required an infracondylar amputation despite anticoagulant treatment.
- The discussion highlights the link between hypercoagulability in critical COVID-19 cases and organ dysfunction, emphasizing that while low molecular weight heparin (LMWH) may improve outcomes, more research is needed on effective prevention and treatment strategies.
Objectives: To assess whether respiratory variation in aortic blood flow peak velocity can predict preload responsiveness in mechanically ventilated and hemodynamically unstable neonates.
Design: Prospective observational diagnostic accuracy study.
Setting: Third-level neonatal ICU.
The objective of this study was to assess the risk of central line-associated bloodstream infection (CLABSI) of ultrasound (US)-guided cannulation of the brachiocephalic vein (BCV) compared to standard epicutaneous cava catheters (ECCs) in preterm infants. This was a retrospective cohort study in preterm infants with a birth weight of less than 1500 g. Each BCV catheter was matched 1:3 with ECCs according to sex, birth weight, and year of insertion.
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- The premature closure of the foramen ovale (FO) is a rare condition linked to high risks of pulmonary hypertension, potentially leading to serious complications like heart failure and fetal death.
- An ultrasound before birth showed a newborn with enlarged right heart chambers, which was confirmed by a postnatal echocardiogram that indicated pulmonary hypertension and an immobile interatrial septum due to a closed FO.
- After nine days of respiratory distress, further echocardiograms showed some improvement in pulmonary hypertension, but mild dysfunction in the left ventricle remained, leading to a decision to use diuretics for treatment, resulting in normalized heart function.
N-terminal-probrain natriuretic peptide as a biomarker of moderate to severe bronchopulmonary dysplasia in preterm infants: A prospective observational study.
Pediatr Pulmonol
August 2018
Article Synopsis
- NT-proBNP levels, an indicator of significant heart conditions in preterm infants, were studied to see if they could predict the risk of developing moderate to severe bronchopulmonary dysplasia (BPD) and/or death.
- In this observational study involving preterm infants born at or before 32 weeks gestation, NT-proBNP was measured at two time points: 48-96 hours and 5-10 days after birth.
- Results showed that higher NT-proBNP levels at 5-10 days were linked to increased risks of BPD and death, suggesting it could be a useful tool for identifying at-risk infants and tailoring treatment plans.
[Impact of screening and treatment of low systemic blood flow in the prevention of severe intraventricular haemorrhage and/or death in pre-term infants].
An Pediatr (Engl Ed)
December 2018
Objective: To assess the effect of a protocolised intervention for low systemic blood flow (SBF) in the occurrence of severe intraventricular haemorrhage (IVH) or death in pre-term infants.
Methods: A study with a quasi-experimental design with retrospective controls was conducted on pre-term infants of less than 30weeks of gestational age, born between January 2016 and July 2017, who were consecutively included in the intervention period. The control cohort included pre-term infants (born between January 2013 and December 2015) matched by gestational age, birth weight, and gender (two controls for each case).
Article Synopsis
- The study evaluates the effectiveness and safety of using ultrasound to guide central venous catheterization in neonates, particularly focusing on the brachiocephalic vein.
- In a sample of 40 procedures, the first attempt success rate was 72.5%, and the overall success rate reached 95%, with minimal complications observed.
- The findings suggest that ultrasound guidance is a viable option for acutely ill neonates, including those with low birth weights, requiring large-bore catheters.