Publications by authors named "Sandra Sinius Pouplier"
Article Synopsis
- The alignment of tissue in whole-slide images (WSI) is essential for both research and clinical purposes, and recent advancements in computing and deep learning have changed how these images are analyzed.
- The ACROBAT challenge was organized to evaluate various WSI registration algorithms using a large dataset of 4,212 WSIs from breast cancer patients, aiming to align tissue stained with different methods.
- The study found that various WSI registration methods can achieve high accuracy and identified specific clinical factors that affect their performance, helping researchers choose and improve their analysis techniques.
Background And Purpose: Calcium electroporation (CaEP) involves injecting calcium into tumour tissues and using electrical pulses to create membrane pores that induce cell death. This study assesses resultant immune responses and histopathological changes in patients with cutaneous metastases.
Patients/materials And Methods: The aimed cohort comprised 24 patients with metastases exceeding 5 mm.
The analysis of FFPE tissue sections stained with haematoxylin and eosin (H&E) or immunohistochemistry (IHC) is essential for the pathologic assessment of surgically resected breast cancer specimens. IHC staining has been broadly adopted into diagnostic guidelines and routine workflows to assess the status of several established biomarkers, including ER, PGR, HER2 and KI67. Biomarker assessment can also be facilitated by computational pathology image analysis methods, which have made numerous substantial advances recently, often based on publicly available whole slide image (WSI) data sets.
View Article and Find Full Text PDFBackground: Survival from many cancer types is steadily increasing, and as a result, a growing number of cancer patients will live with other chronic diseases, of which diabetes is one of the most prevalent. This study aims to describe the impact of cancer on health outcomes in patients with type 2 diabetes and to compare the effectiveness of a multifactorial intervention in diabetes patients with and without cancer.
Methods: The randomized controlled trial Diabetes Care in General Practice (DCGP) included 1381 patients newly diagnosed with type 2 diabetes.