Entrepreneurship catalyzes economic growth; it generates jobs, advances the economy and solves global challenges. Hence, it is crucial to understand the factors contributing to entrepreneurship and entrepreneurs' development. While many studies have investigated intrapersonal factors for entrepreneurial tendencies, the present study focuses on a critical yet often overlooked interpersonal aspect: attachment orientations.
View Article and Find Full Text PDFThe COVID-19 crisis has caused severe psychological distress. Governments have been trying to fight the outbreak, inter alia, by enacting various restrictions to maintain social distancing. However, compliance with restrictions depends upon different interpersonal variables.
View Article and Find Full Text PDFWhy did COVID-19 hit some countries harder than others? While this question is usually answered based on demographics (e. g., population age), health policy (e.
View Article and Find Full Text PDFFriedreich's ataxia (FDRA) is the most common inherited ataxia worldwide, caused by homozygous GAA expansions in the FXN gene. Patients usually have early onset ataxia, areflexia, Babinski sign, scoliosis and pes cavus, but at least 25 % of cases have atypical phenotypes. Disease begins after the age of 25 in occasional patients (late-onset Friedreich ataxia (LOFA)).
View Article and Find Full Text PDFIntellectual disability affects approximately 1-3% of the population and can be caused by genetic and environmental factors. Although many studies have investigated the etiology of intellectual disability in different populations, few studies have been performed in middle-income countries. The present study estimated the prevalence of genetic causes related to intellectual disability in a cohort of children from a city in south Brazil who were followed from birth.
View Article and Find Full Text PDFThe polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene are associated with leukemogenesis. In order to investigate the influence of two polymorphisms in the MTHFR gene, 677C>T and 1298A>C, on the risk of acute lymphoblastic leukemia (ALL) we performed a case-control study in children from different Brazilians' regions. Genotyping of 176 ALL and 199 unselected healthy subjects was performed using PCR-RFLP assay.
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