Microbiota unbalance in relation to high-risk human papillomavirus cervical infection.

Objectives: To assess vaginal dysfunction using basic vaginal states and the presence of lactobacillary microbiota in patients with human papillomavirus (HPV) infection with no squamous intra-epithelial lesions (SIL), with low-grade squamous intra-epithelial lesions (L-SIL), and with high-grade squamous intra-epithelial lesions (H-SIL) or squamous cell carcinoma compared with a control group (HPV-negative); to establish the prevalence of bacterial vaginosis, candidiasis, and trichomoniasis in the different age groups; and to characterize the species of lactobacilli according to the type of lesion.

Methods: A cross-sectional study was carried out of patients who underwent clinical examination and collection of vaginal fornixes to study basic vaginal states and culture. Species identification of lactobacilli was performed by mass spectrometry.

Vaginal States: Detection of Conversion Processes in Women Using Contraception and Characterization of Vaginal Lactobacillus Species.

Background: The vaginal microenvironment, regulated by an immune system, can be protected or altered by many factors, including contraceptive methods.

Objective: The objective of this study is to evaluate the impact of contraceptive methods on the basic vaginal states (BVSs) and to identify culturable vaginal Lactobacillus species.

Methods: This is a prospective, consecutive, longitudinal, and descriptive study.

Biochemical profiling study in umbilical cord blood in mothers with metabolic disorders.

Background: During pregnancy metabolic disorders that affect differently the fetus, are known. These could be early or late disorders.

Objectives: To analyze different biochemical parameters in umbilical cord blood (UCB) of healthy and pathological newborns from mothers with metabolic disorders.