Investigation of genetic polymorphisms in genes encoding growth factors and dental pulp calcification in orthodontic patients.

Background And Objectives: Pulp calcification is associated with many factors and triggers, including individual genetic predisposition and orthodontic forces. This study aimed to investigate whether genetic polymorphisms in are associated with a risk of dental pulp calcifications in orthodontic patients.

Materials And Methods: Digital orthopantomography (OPG) and genomic DNA from 132 patients were analyzed in this cross-sectional study.

BMP2 rs1005464 is associated with mandibular condyle size variation.

This study aimed to evaluate the association between single nucleotide polymorphisms (SNPs) in endochondral development-related genes and mandibular condyle shape, size, volume, and symmetry traits. Cone-beam Computed Tomographies and genomic DNA from 118 individuals were evaluated (age range: 15-66 years). Data from twelve 3D landmarks on mandibular condyles were submitted to morphometric analyses including Procrustes fit, principal component analysis, and estimation of centroid sizes and fluctuating asymmetry scores.

Single nucleotide polymorphisms in inducible nitric oxide synthase gene are not associated with persistent apical periodontitis.

The aim of this study was to investigate whether there is an association between inducible in single nucleotide polymorphisms in nitric oxide synthase (rs2297518 and rs2779249) and persistent apical periodontitis. A total of 291 Brazilian subjects were included: 125 with signs/symptoms of persistent apical periodontitis and 166 with root canal-treated teeth exhibiting healthy perirradicular tissues. Endodontically treated patients were followed up after 1 year.

Association between single-nucleotide polymorphisms in serotonin receptor 2A and melatonin receptor 1A genes and pain after root canal treatment.

Aim: This study aimed to investigate whether single-nucleotide polymorphisms (SNPs) in the genes encoding 5-HTR2A (5-Hydroxytryptamine (serotonin) receptor 2A) and MTNR1A (melatonin receptor 1A) may contribute to postoperative pain perception after root canal treatment. We hypothesised that SNPs in HTR2A and MTNR1A genes were associated with postoperative pain after root canal treatment.

Methodology: This genetic cohort study enrolled patients with single-rooted teeth diagnosed with pulp necrosis and asymptomatic apical periodontitis before root canal treatment.

Do Antimicrobial Photodynamic Therapy and Low-Level Laser Therapy Influence Oral Health-Related Quality of Life After Molar Extraction?

Purpose: Most individuals experience significant deterioration in their oral health-related quality of life (OHRQoL) in the first few days after tooth extraction. This study aimed to evaluate the impact of antimicrobial photodynamic therapy (aPDT) and low-level laser therapy (LLLT) protocols on OHRQoL after extraction of lower molars.

Methods: The investigators designed a double-blind, randomized controlled clinical trial study.

Dental trauma in primary dentition and the importance of its preservation until the eruption of permanent successor: a 6-year follow-up case report.

Traumatic dental injuries (TDIs) are a public health concern that requires special attention in primary dentition due to the sequel that can be originated in permanent dentition. This paper aims to report a dental trauma injury highlighting the importance of follow-up the traumatized primary tooth until the eruption of its permanent successor. A 3-year-old female patient referred to a Dental Trauma Care Program (DTCP) in a Brazilian Public University after falling from her own height with the involvement of the deciduous maxillary left central incisor.

Aesthetic-functional reconstruction of dental fracture and its impact on the psychosocial aspect.

Traumatic dental injury (TDI) constitutes a public health concern. This injury occurs mainly in anterior teeth and brings disadvantageous psychosocial consequences that affect adolescents, as well as impairing their speech and eating habits. A healthy smile and facial aesthetic have an influence on social interaction, especially in the way individuals are seen, felt, and perceived by other people.

Improvement on OHRQoL after endodontic treatment associated with aPDT in traumatized primary teeth: a 12-month follow-up case report.

Dental trauma is often associated with a negative impact on the oral health-related quality of life (OHRQoL). The management of traumatized teeth is a challenge in the daily pediatric dentistry clinic, due to the sequels generated over time. Pulp necrosis is a frequent sequel that requires a pulpectomy.

The impact of traumatic dental injury on sensory perception and oral health-related quality of life of a child/adolescent before and after the treatment with aesthetic prosthesis: case report.

Children and adolescents are most frequently affected by Traumatic Dental Injuries (TDIs). Scientific evidence shows that TDIs have a negative impact on the oral health-related quality of life (OHRQoL) of children/adolescents and their families. This article aimed to report two cases of avulsion and how the treatment influenced the oral sensory perception and OHRQoL.

The clinical practice of Pediatric Dentistry post-COVID-19: The current evidences.

The Severe Acute Respiratory Syndrome (SARS) caused by SARS-CoV-2 virus has quickly spread all over the world, directly affecting the dentistry practice. This study aimed to perform a literature review about the current evidences on biosafety practices and clinical recommendations regarding the return to the elective dental care in the practice of Pediatric dentistry. An electronic search was performed in PubMed, Scopus, Web of Science and Grey literature databases using the terms "Pediatric dentistry" and "COVID-19".