Publications by authors named "Sandra Margarita Ramirez-Meza"
Expression of the receptor of advanced glycation end-products (RAGE) and membranal location in peripheral blood mononuclear cells (PBMC) in obesity and insulin resistance.
Elizabeth Del Carmen Ruelas Cinco Bertha Ruíz Madrigal José Alfredo Domínguez Rosales Montserrat Maldonado González Lucía De la Cruz Color
Iran J Basic Med Sci
June 2019
Objectives: The present study aimed to evaluate the receptor of advanced glycation end-products (RAGE), NF-kB, NRF2 gene expression, and RAGE cell distribution in peripheral blood mononuclear cells (PBMC) in subjects with obesity and IR compared with healthy subjects.
Materials And Methods: The mRNA expression levels of RAGE, NF-kB, NRF2, and GAPDH were determined in PBMC by qPCR in 20 obese (OB), 17 obese with insulin resistance (OB-IR), and 20 healthy subjects (HS), matched by age and sex. RAGE protein expression and its localization were determined by Western Blot and immunocytochemistry (ICC) analysis, total soluble RAGE (sRAGE) and MCP-1 plasma levels by ELISA.
Association of the PNPLA2, SCD1 and Leptin Expression with Fat Distribution in Liver and Adipose Tissue From Obese Subjects.
Lucía De la Cruz-Color Zamira Helena Hernández-Nazará Montserrat Maldonado-González Eliseo Navarro-Muñíz José Alfredo Domínguez-Rosales
Exp Clin Endocrinol Diabetes
November 2020
Article Synopsis
- The study examines how insulin and leptin influence fat tissue expansion through specific genes and enzymes connected to fat storage and breakdown.
- Data was collected from 38 individuals who underwent gallbladder surgery, analyzing gene expression in liver and adipose tissues alongside measures of body fat and composition.
- Results showed higher expression of certain genes linked to fat storage in obese individuals compared to lean and overweight counterparts, indicating a relationship between these genes, fat distribution, and leptin levels.