Publications by authors named "Sandra M Polin"
Article Synopsis
- The study aimed to evaluate how effective preoperative measurements are in detecting complete response to chemotherapy and assessing any remaining disease in women with locally advanced breast cancer.
- The research involved analyzing data from the American College of Radiology Imaging Network 6657 Trial, focusing on various imaging methods like MRI and mammography to measure tumor size before surgery.
- Findings showed that MRI's longest diameter measurement was the most accurate for determining treatment response and correlating with final pathology, outperforming other methods like mammography and clinical exams.
Purpose: To estimate the accuracy of predicting response to neoadjuvant chemotherapy (NACT) in patients with locally advanced breast cancer using MR spectroscopy (MRS) measurements made very early in treatment.
Materials And Methods: This prospective Health Insurance Portability and Accountability Act (HIPAA)-compliant protocol was approved by the American College of Radiology and local-site institutional review boards. One hundred nineteen women with invasive breast cancer of ≥3 cm undergoing NACT were enrolled between September 2007 and April 2010.
Purpose: To evaluate volumetric magnetic resonance (MR) imaging for predicting recurrence-free survival (RFS) after neoadjuvant chemotherapy (NACT) of breast cancer and to consider its predictive performance relative to pathologic complete response (PCR).
Materials And Methods: This HIPAA-compliant prospective multicenter study was approved by institutional review boards with written informed consent. Women with breast tumors 3 cm or larger scheduled for NACT underwent dynamic contrast-enhanced MR imaging before treatment (examination 1), after one cycle (examination 2), midtherapy (examination 3), and before surgery (examination 4).