Publications by authors named "Sandra I Salazar-Garcia"
Sea anemone venom composition includes polypeptide and non-proteins molecules. Cytolytic components have a high biotechnological and biomedical potential for designing new molecular tools. Sea anemone venom locates in glandular cells from ectoderm and sub-cellular structures called nematocysts, both of which are distributed throughout the sea anemone body.
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- Pore-forming proteins (PFP) from sea anemone venom can damage cell membranes, showing potential for medical use in cancer treatment and biosensors.
- The study involved partial purification and sequencing of a PFP from Verrill (1869), along with testing its cytolytic effects on different mammal erythrocytes and human lung carcinoma cells.
- Results showed specific protein concentrations that led to hemolysis and cell death, confirming the presence of a PFP that causes cytotoxic effects in the studied cells.