Publications by authors named "Sandra Guerard"

Background/aim: It is difficult to characterize the impact behavior of mouthguards on the basis of their components. Impact behavior tests should be performed on mouthguard formed to simulate their intra-oral performance. The aim of this study was to compare the impact behavior of six models of mouthguards using a standardized experimental protocol.

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  • The study focused on how the nonlinear elastic properties of human cortical bone change when a small crack is introduced, using 14 bone specimens and nonlinear resonant ultrasound spectroscopy (NRUS) for measurement.
  • A 500 µm crack was created in the specimens, and researchers observed significant increases in the nonlinear elastic coefficient αf after crack propagation, while other parameters remained stable.
  • It was found that the nonlinear elastic behavior of the bone is more pronounced in hydrated conditions, and there is a strong correlation between the crack length and the nonlinear elastic parameter αf in both dry and wet conditions.
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  • - Recent advancements in biomaterials have improved artificial ligaments, increasing interest in their use for anterior cruciate ligament (ACL) reconstructions.
  • - A study tested four types of femoral ACL fixations using a new system called LARS™ AC, comparing their strength, slippage, and failure modes under static loads.
  • - The transversal fixation showed the highest load capacity and potential for better clinical outcomes, even though it experienced more graft slippage compared to other methods tested.
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This study examined whether the thermo-modeling process suits the thermal properties of the material constituting mouth-formed mouthguards (MGs). Five mouth-formed MGs were compared: four commercially available MGs (SDI™, Gel Nano™, Opro Shield Gold™, and Kipsta R300™) and one prototype. Differential scanning calorimetry was used to determine melting (T(m)) and crystallization (T(c)) temperatures and specific fusion and crystallization enthalpies (∆H(f) and ∆H(c) (J/g)).

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  • The study assessed the effectiveness of nonlinear resonant ultrasound spectroscopy (NRUS) in detecting microdamage in human cortical bone caused by cyclic four-point bending fatigue.
  • Bone specimens were subjected to controlled fatigue cycles, and NRUS measurements examined the relationship between nonlinear elastic behavior and microdamage accumulation throughout the process.
  • Findings indicated a significant correlation between increases in nonlinear hysteretic elastic behavior and the emergence of short microcracks, suggesting that NRUS can be a valuable tool for monitoring early stages of bone microdamage.
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This study investigates the impact of polystyrene sodium sulfonate (PolyNaSS) grafting onto the osseo-integration of a polyethylene terephthalate artificial ligament (Ligament Advanced Reinforcement System, LARS™) used for Anterior Cruciate Ligament (ACL). The performance of grafted and non-grafted ligaments was assessed in vitro by culturing human osteoblasts under osteogenic induction and this demonstrated that the surface modification was capable of up-regulating the secretion of ALP and induced higher level of mineralisation as measured 6 weeks post-seeding by Micro-Computed Tomography. Grafted and non-grafted LARS™ were subsequently implanted in an ovine model for ACL reconstruction and the ligament-to-bone interface was evaluated by histology and biomechanical testings 3 and 12 months post-implantation.

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  • This study evaluated the tissue integration and mechanical properties of the LARS artificial ligament used for replacing the anterior cruciate ligament (ACL) in a sheep model.
  • Researchers found that tissue ingrowth only happened where the artificial ligament touched native tissues, and 40% of the explanted knees showed ligament wear.
  • While the LARS AC performed reasonably well clinically over a year, its mechanical strength was significantly below that of a normal ACL, indicating limitations for complete ACL replacement.
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A significant risk of femoral neck (FN) fracture exists for men and women with an areal bone mineral density (aBMD) higher than the osteoporotic range, as measured with dual-energy X-ray absorptiometry (DXA). Separately measuring the cortical and trabecular FN compartments and combining the results would likely be a critical aspect of enhancing the diagnostic capabilities of a new technique. Because the cortical shell determines a large part of FN strength a novel quantitative ultrasound (QUS) technique that probes the FN cortical compartment was implemented.

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A mini-compression jig was built to perform in situ tests on bovine trabecular bone monitored by micro-MRI. The MRI antenna provided an isotropic resolution of 78 microm that allows for a volume correlation method to be used. Three-dimensional displacement fields are then evaluated within the bone sample during the compression test.

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