Publications by authors named "Sandra Garcia-Botella"
P-element-induced wimpy testis (PIWI) proteins have been described in several cancers. PIWIL1 and PIWIL2 have been recently evaluated in pancreatic cancer, and elevated expression of PIWIL2 conferred longer survival to patients. However, PIWIL3's and PIWIL4's role in carcinogenesis is rather controversial, and their clinical implication in pancreatic cancer has not yet been investigated.
View Article and Find Full Text PDFArticle Synopsis
- The COVID-19 pandemic, caused by the SARS-CoV-2 virus, has led to a need for surgical procedures among patients with confirmed or suspected infections.
- Special precautions are necessary to limit virus transmission, protect healthcare staff, and prevent postoperative complications.
- The document outlines key principles for managing these patients during both their evaluation and surgical treatment.
Pancreatic cancer is a highly aggressive manifestation of cancer, and currently presents poor clinical outcome due to its late diagnosis with metastasic disease. Surgery is the only approach with a curative intend; however, the survival rates seen in this type of patient are still low. After surgery, there is a lack of predictive prognosis biomarkers to predict treatment response and survival to establish a personalized medicine.
View Article and Find Full Text PDFIntroduction: Ampullary adenocarcinoma seems less aggressive than other pancreato-biliary neoplasms. The aim of this study is to define determining prognostic factors.
Material And Methods: Retrospective case series from a large tertiary Hospital including all patients diagnosed with ampullary adenocarcinoma who underwent cephalic pancreatoduodenectomy with curative intent.