Publications by authors named "Sandra Fernandes Martins"
Article Synopsis
- Colorectal cancer (CRC) is a major global health issue, characterized by high glycolysis rates in cancer cells, leading to lactic acid production that is exported via monocarboxylate transporters (MCTs).
- The study analyzed the expression of MCT1, MCT4, CD147, and GLUT1 in primary CRC and its metastases, using immunohistochemistry on human samples.
- Findings showed overexpression of these proteins in primary CRC and metastases, indicating the importance of MCTs as potential biomarkers and targets for treatment in CRC.
