Cognitive behavioural therapy for fatigue in patients with multiple sclerosis: A systematic review and meta-analysis.

Background: Treatment of fatigue is important for many patients with multiple sclerosis (MS). While pharmacological options have not shown consistent benefit, psychological interventions offer another avenue of treatment. Cognitive behavioural therapy (CBT) involves strategies to change maladaptive cognition and illness behaviours that modulate how patients with MS respond to fatigue.

The coexistence of diabetic retinopathy and diabetic nephropathy is associated with worse kidney outcomes.

Background: Up to 50-60% of patients with diabetes have non-diabetic kidney disease (NDKD) on kidney biopsy. Diabetic retinopathy (DR) is a microvascular complication of diabetes frequently associated with diabetic nephropathy (DN). The objective of the current study was to investigate the kidney outcomes and survival in patients with biopsy diagnoses of DN and NDKD according to the presence of DR.

Factor H-Related Protein 1 Drives Disease Susceptibility and Prognosis in C3 Glomerulopathy.

Background: C3 glomerulopathy (C3G) is a heterogeneous group of chronic renal diseases characterized predominantly by glomerular C3 deposition and complement dysregulation. Mutations in factor H-related (FHR) proteins resulting in duplicated dimerization domains are prototypical of C3G, although the underlying pathogenic mechanism is unclear.

Methods: Using and assays, we performed extensive characterization of an FHR-1 mutant with a duplicated dimerization domain.

Risk factors for non-diabetic renal disease in diabetic patients.

Background: Diabetic patients with kidney disease have a high prevalence of non-diabetic renal disease (NDRD). Renal and patient survival regarding the diagnosis of diabetic nephropathy (DN) or NDRD have not been widely studied. The aim of our study is to evaluate the prevalence of NDRD in patients with diabetes and to determine the capacity of clinical and analytical data in the prediction of NDRD.

Dexmedetomidine for Improved Quality of Emergence From General Anesthesia: A Dose-Finding Study.

Background: Dexmedetomidine provides smooth and hemodynamically stable emergence at the expense of hypotension, delayed recovery, and sedation. We investigated the optimal dose of dexmedetomidine for prevention of cough, agitation, hypertension, tachycardia, and shivering, with minimal side effects.

Methods: In this prospective, randomized, double-blind trial, 216 adult patients were randomly assigned to dexmedetomidine 1 µg/kg (D 1), 0.

Diagnosis and laparoscopic management of retrocaval ureter: A review of the literature and our case series.

Objectives: To expose the diagnosis and the different laparoscopic approaches for the surgical management of patients with retrocaval ureter (RCU) and to share our experience on two cases.

Methods: Updated literature review on Pubmed and debating personal experiences including ours (double j stent insertion before the surgery, use of 4 trocards, transperitoneal approach, pyelopyelostomy for the anastomosis…), concerning the laparoscopic treatment of the RCU.

Results: Laparoscopic treatment of RCU is a recommended management for many reasons: less blood loss during the surgery, a shorter hospital stay, less postoperative pain and superior esthetic results with excellent functional results.

Bilateral laparoscopic ureterolysis using hydrodissection in retroperitoneal fibrosis: a new application of an old technique.

To describe our new laparoscopic approach in ureterolysis using the ERBEJET 2 device to hydrodissect the ureters in idiopathic retroperitoneal fibrosis. Bilateral laparoscopic ureterolysis was done after medical therapy failure (steroids) in a 47 year old patient with retroperitoneal fibrosis. Ureteral stents were placed before surgery.

Arteriovenous fistulae after renal biopsy: diagnosis and outcomes using Doppler ultrasound assessment.

Background: Percutaneous renal biopsy (PRB) is an important technique providing relevant information to guide diagnosis and treatment in renal disease. As an invasive procedure it has complications. Most studies up to date have analysed complications related to bleeding.

Effectiveness of mycophenolate mofetil in C3 glomerulonephritis.

C3 glomerulonephritis is a clinicopathologic entity defined by the presence of isolated or dominant deposits of C3 on immunofluorescence. To explore the effect of immunosuppression on C3 glomerulonephritis, we studied a series of 60 patients in whom a complete registry of treatments was available over a median follow-up of 47 months. Twenty patients had not received immunosuppressive treatments.

Musculoskeletal physiotherapists' perceptions of non-responsiveness to treatment for cervicogenic headache.

Cervicogenic headache (CH) is a debilitating pain problem, estimated to affect 13-17% of the population with chronic headache. Physiotherapy can improve this condition in 75% of patients but the remaining 25% are unresponsive to treatment, and to date researchers have been unable to identify predictors of non-responsiveness. The aim of this study was to seek both consensus and alternative accounts by examining the perceptions of experienced musculoskeletal physiotherapists regarding the features associated with non-responsiveness to treatment in adults and children with CH.

Intakes of essential n-6 and n-3 polyunsaturated fatty acids among pregnant Canadian women.

Background: Fetal growth requires n-3 docosahexaenoic acid (DHA), which is derived from the essential n-3 fatty acids in the maternal diet. DHA is accumulated in the developing brain and is critical for normal neural and visual function. Available estimates suggest that 67 mg DHA/d is accumulated by the fetus during the third trimester of gestation.

Bakery foods are the major dietary source of trans-fatty acids among pregnant women with diets providing 30 percent energy from fat.

Objective: To estimate intake and identify major dietary sources of trans-fatty acids consumed by healthy, pregnant women.

Design: Cross-sectional prospective study using a food intake questionnaire designed specifically to estimate trans-fatty acid intakes calculated from a trans-fatty acid food database developed by food analysis.

Subjects/setting: Healthy, pregnant women (n=60) were recruited in Vancouver, BC, Canada.