Publications by authors named "Sandra E Steel"
Article Synopsis
- Vascular endothelial growth factor (VEGF) has roles both in promoting blood vessel formation and in regulating the immune response, particularly in glioblastoma.
- Treatment of glioblastoma patients with radiation, temozolomide (TMZ), and bevacizumab (BEV) led to a significant decrease in regulatory T cells (Tregs) but did not change their proportion relative to other immune cells.
- Additionally, while there were decreases in certain T cell populations, levels of VEGF and placental growth factor (PlGF) in the blood increased, suggesting potential implications for combining immunotherapy with anti-angiogenic treatments.