Publications by Sandra E Linder

Publications by authors named "Sandra E Linder"

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Protein recoding by ADAR1-mediated RNA editing is not essential for normal development and homeostasis.

Jacki E Heraud-Farlow Alistair M Chalk Sandra E Linder Qin Li Scott Taylor

Genome Biol

September 2017

Background: Adenosine-to-inosine (A-to-I) editing of dsRNA by ADAR proteins is a pervasive epitranscriptome feature. Tens of thousands of A-to-I editing events are defined in the mouse, yet the functional impact of most is unknown. Editing causing protein recoding is the essential function of ADAR2, but an essential role for recoding by ADAR1 has not been demonstrated.

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