Publications by authors named "Sandra Diez-Garcia"

Article Synopsis
  • A new methodology combining synchrotron radiation techniques and data mining has improved the assessment of dental enamel remineralization.
  • The study focuses on using controlled ion release from ion-exchange resins in the presence of amelogenin, which aids in tooth enamel mineralization with essential ions like Ca, PO, and F.
  • Analysis of remineralized tooth samples showed that the treated fluorapatite layer mimicked natural enamel structure, benefiting from amelogenin's role in guiding crystal growth and maintaining a pure mineral composition.
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This study aims to develop an innovative dental product to remineralize dental enamel by a proper combination of ion-exchange resins as controlled release of mineral ions that form dental enamel, in the presence of amelogenin to guide the appropriate crystal growth. The novel product proposed consists of a combination of ion-exchange resins (weak acid and weak base) individually loaded with the remineralizing ions: Ca, PO and F, also including Zn in a minor amount as antibacterial, together with the protein amelogenin. Such cocktail provides onsite controlled release of the ions necessary for enamel remineralization due to the weak character of the resins and at the same time, a guiding tool for related crystal growth by the indicated protein.

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