Development of a new definition of maternal near miss based on organ dysfunction in Latin America and the Caribbean: A prospective multicenter cohort study.

Background: There has been debate over whether the existing World Health Organization (WHO) criteria accurately represent the severity of maternal near misses.

Objective: This study assessed the diagnostic accuracy of two WHO clinical and laboratory organ dysfunction markers for determining the best cutoff values in a Latin American setting.

Methods: A prospective multicenter cohort study was conducted in five Latin American countries.

Fast g-CN sonocoated activated carbon for enhanced solar photocatalytic oxidation of organic pollutants through Adsorb & Shuttle process.

To solve low mass transfer in photocatalytic technology for water treatment, the combination of photoactive nanoparticles with highly adsorptive materials has been regarded as a successful approach. The optimization of photoactive particle coating in terms of dispersion on the surface of adsorbing support is the main key to reach a maximum synergism for pollutants removal. This study discusses the coating of as-prepared biomass based activated carbon by g-CN using three routes, namely ball milling (AC-CN@BM), physical stirring (AC-CN@Phy) and ultrasonic assisted coating (AC-CN@US).

Valorization of lignocellulosic biomass into sustainable materials for adsorption and photocatalytic applications in water and air remediation.

An exponential rise in global pollution and industrialization has led to significant economic and environmental problems due to the insufficient application of green technology for the chemical industry and energy production. Nowadays, the scientific and environmental/industrial communities push to apply new sustainable ways and/or materials for energy/environmental applications through the so-called circular (bio)economy. One of today's hottest topics is primarily valorizing available lignocellulosic biomass wastes into valuable materials for energy or environmentally related applications.

Radical-Mediated Photocatalysis for Lignocellulosic Biomass Conversion into Value-Added Chemicals and Hydrogen: Facts, Opportunities and Challenges.

Photocatalytic biomass conversion into high-value chemicals and fuels is considered one of the hottest ongoing research and industrial topics toward sustainable development. In short, this process can cleave C -O/C -C bonds in lignin to aromatic platform chemicals, and further conversion of the polysaccharides to other platform chemicals and H . From the chemistry point of view, the optimization of the unique cooperative interplay of radical oxidation species (which are activated via molecular oxygen species, ROSs) and substrate-derived radical intermediates by appropriate control of their type and/or yield is key to the selective production of desired products.

Combined conversion of lignocellulosic biomass into high-value products with ultrasonic cavitation and photocatalytic produced reactive oxygen species - A review.

The production of high-value products from lignocellulosic biomass is carried out through the selective scission of crosslinked CC/CO bonds. Nowadays, several techniques are applied to optimize biomass conversion into desired products with high yields. Photocatalytic technology has been proven to be a valuable tool for valorizing biomass at mild conditions.

O/HO and UV-C light irradiation treatment of oil sands process water.

The oil sands industry generates large volumes of oil sands process water (OSPW). There is an urgent need for OSPW treatment to reduce process water inventories and to support current reclamation approaches. This study discusses how efficient ozone (O)-based combined advanced oxidation processes (AOPs), including hydrogen peroxide (HO) and UV-C, are at achieving mineralization while reducing the toxicity arising from such organic components as naphthenic acids (NAs) in OSPW.

Quantitative Proteomic Analysis of Cervical Cancer Tissues Identifies Proteins Associated With Cancer Progression.

Background/aim: To date, several proteomics studies in cervical cancer (CC) have focused mainly on squamous cervical cancer (SCC). Our study aimed to discover and clarify differences in SCC and CAD that may provide valuable information for the identification of proteins involved in tumor progression, in CC as a whole, or specific for SCC or CAD.

Materials And Methods: Total protein extracts from 15 individual samples corresponding to 5 different CC tissue types were compared with a non-cancerous control group using bidimensional liquid chromatography-mass spectrometry (2D LC-MS/MS), isobaric tags for relative and absolute quantitation (ITRAQ), principal component analysis (PCA) and gene set enrichment analysis (GSEA).

Symptomology following mRNA vaccination against SARS-CoV-2.

Despite demonstrated efficacy of vaccines against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the causative agent of coronavirus disease-2019 (COVID-19), widespread hesitancy to vaccination persists. Improved knowledge regarding frequency, severity, and duration of vaccine-associated symptoms may help reduce hesitancy. In this prospective observational study, we studied 1032 healthcare workers who received both doses of the Pfizer-BioNTech SARS-CoV-2 mRNA vaccine and completed post-vaccine symptom surveys both after dose 1 and after dose 2.

Determining the effects of Class I landfill leachate on biological nutrient removal in wastewater treatment.

The disposal of landfill leachate is a chronic problem facing the municipal solid waste industry. The composition of landfill leachate is highly variable and often dependent on site-specific conditions. Due to the potentially disruptive impact on wastewater treatment processes, wastewater treatment plants (WWTP) are reluctant to accept landfill leachate for co-treatment.

Produced water treatment by advanced oxidation processes.

Different Advanced Oxidation Processes (AOPs) such as photocatalysis, Fenton-based processes and ozonation were studied to include one of these technologies within an integrated solution for produced water (PW) polishing. Synthetic PW was prepared adding toluene, xylene, naphthalene, phenol, acetic and malonic acids to a seawater matrix. Despite that in all AOPs studied in this work BTEX and naphthalene were removed, the efficiency (in terms of TOC removal) of each treatment varied largely.

Development of a Telehealth-Coordinated Intervention to Improve Access to Community-Based Mental Health.

Objective: To develop an intervention to improve the mental health referral and care process for children referred by primary care providers (PCPs) to community mental health clinics (MHCs) using a community partnered approach.

Design: A Project Working Group (PWG) with representatives from each partner organization met monthly for 6 months.

Setting: Multi-site federally qualified health center (FQHC) and two community MHCs in Los Angeles county.

Feasibility and Acceptability in a Community-Partnered Implementation of CenteringParenting for Group Well-Child Care.

Background: In a community-academic partnership, we implemented a group-based model for well-child care (WCC) (CenteringParenting) and conducted a pilot test for feasibility and acceptability among families at a federally qualified health center (FQHC).

Methods: The FQHC implemented CenteringParenting for all WCC visits in the first year of life, starting at the 2-week visit. Over a 14-month time period, parents from each new CenteringParenting group were enrolled into the study.

Displacers improve the selectivity of phosphopeptide enrichment by metal oxide affinity chromatography.

Background: A key process in cell regulation is protein phosphorylation, which is catalyzed by protein kinases and phosphatases. However, phosphoproteomics studies are difficult because of the complexity of protein phosphorylation and the number of phosphorylation sites.

Methods: We describe an efficient approach analyzing phosphopeptides in single, separated protein by two-dimensional gel electrophoresis.

Lysine acetylation stoichiometry and proteomics analyses reveal pathways regulated by sirtuin 1 in human cells.

Lysine acetylation is a widespread posttranslational modification affecting many biological pathways. Recent studies indicate that acetylated lysine residues mainly exhibit low acetylation occupancy, but challenges in sample preparation and analysis make it difficult to confidently assign these numbers, limiting understanding of their biological significance. Here, we tested three common sample preparation methods to determine their suitability for assessing acetylation stoichiometry in three human cell lines, identifying the acetylation occupancy in more than 1,300 proteins from each cell line.

Well-Child Care Redesign: A Mixed Methods Analysis of Parent Experiences in the PARENT Trial.

Background: Parent-focused Redesign for Encounters, Newborns to Toddlers (PARENT), is a well-child care (WCC) model that has demonstrated effectiveness in improving the receipt of comprehensive WCC services and reducing emergency department utilization for children aged 0 to 3 in low-income communities. PARENT relies on a health educator ("parent coach") to provide WCC services; it utilizes a Web-based previsit prioritization/screening tool (Well-Visit Planner) and an automated text message reminder/education service. We sought to assess intervention feasibility and acceptability among PARENT trial intervention participants.

Integrated processes for produced water polishing: Enhanced flotation/sedimentation combined with advanced oxidation processes.

In this study, bench scale dissolved air flotation (DAF) and settling processes have been studied and compared to a novel flotation technology based on the use of glass microspheres of limited buoyancy and its combination with conventional DAF, (Enhanced DAF or E-DAF). They were evaluated as pretreatments for advanced oxidation processes (AOPs) to polish produced water (PW) for reuse purposes. Settling and E-DAF without air injection showed adequate turbidity and oil and grease (O&G) removals, with eliminations higher than 87% and 90% respectively, employing 70 mg L of FeCl and 83 min of settling time, and 57.

A Parent Coach Model for Well-Child Care Among Low-Income Children: A Randomized Controlled Trial.

Objective: The goal of this study was to examine the effects of a new model for well-child care (WCC), the Parent-focused Redesign for Encounters, Newborns to Toddlers (PARENT), on WCC quality and health care utilization among low-income families.

Methods: PARENT includes 4 elements designed by using a stakeholder-engaged process: (1) a parent coach (ie, health educator) to provide anticipatory guidance, psychosocial screening and referral, and developmental/behavioral guidance and screening at each well-visit; (2) a Web-based tool for previsit screening; (3) an automated text message service to provide periodic, age-specific health messages to families; and (4) a brief, problem-focused encounter with the pediatric clinician. The Promoting Healthy Development Survey-PLUS was used to assess receipt of recommended WCC services at 12 months' postenrollment.

Size and aspect ratio control of Pd₂Sn nanorods and their water denitration properties.

Monodisperse Pd2Sn nanorods with tuned size and aspect ratio were prepared by co-reduction of metal salts in the presence of trioctylphosphine, amine, and chloride ions. Asymmetric Pd2Sn nanostructures were achieved by the selective desorption of a surfactant mediated by chlorine ions. A preliminary evaluation of the geometry influence on catalytic properties evidenced Pd2Sn nanorods to have improved catalytic performance.

Analysis and prediction of pathways in HeLa cells by integrating biological levels of organization with systems-biology approaches.

It has recently begun to be considered that cancer is a systemic disease and that it must be studied at every level of complexity using many of the currently available approaches, including high-throughput technologies and bioinformatics. To achieve such understanding in cervical cancer, we collected information on gene, protein and phosphoprotein expression of the HeLa cell line and performed a comprehensive analysis of the different signaling pathways, transcription networks and metabolic events in which they participate. A total expression analysis by RNA-Seq of the HeLa cell line showed that 19,974 genes were transcribed.

Evaluation of a fotonovela to increase depression knowledge and reduce stigma among Hispanic adults.

Fotonovelas-small booklets that portray a dramatic story using photographs and captions-represent a powerful health education tool for low-literacy and ethnic minority audiences. This study evaluated the effectiveness of a depression fotonovela in increasing depression knowledge, decreasing stigma, increasing self-efficacy to recognize depression, and increasing intentions to seek treatment, relative to a text pamphlet. Hispanic adults attending a community adult school (N = 157, 47.

Vitamin D and cardiovascular disease: potential role in health disparities.

Cardiovascular disease (CVD), which includes coronary artery disease and stroke, is the leading cause of mortality in the nation. Excess CVD morbidity and premature mortality in the African American community is one of the most striking examples of racial/ ethnic disparities in health outcomes. African Americans also suffer from increased rates of hypovitaminosis D, which has emerged as an independent risk factor for all-cause and cardiovascular mortality.

Focus group evaluation of "Secret Feelings": a depression fotonovela for Latinos with limited English proficiency.

In this study, the authors examined reactions of Latino adults with limited English proficiency (LEP) to a culturally and linguistically adapted depression fotonovela, titled "Secret Feelings." Fotonovelas are popular health education tools that use posed photographs, text bubbles with simple text, and dramatic narratives to engage audiences and raise their awareness and knowledge about specific health issues. Four focus groups (N = 32) were conducted at an adult school program (e.

Systems biology of bacterial nitrogen fixation: high-throughput technology and its integrative description with constraint-based modeling.

Background: Bacterial nitrogen fixation is the biological process by which atmospheric nitrogen is uptaken by bacteroids located in plant root nodules and converted into ammonium through the enzymatic activity of nitrogenase. In practice, this biological process serves as a natural form of fertilization and its optimization has significant implications in sustainable agricultural programs. Currently, the advent of high-throughput technology supplies with valuable data that contribute to understanding the metabolic activity during bacterial nitrogen fixation.

Hydrogen substitutes for the in situ generation of H2O2: an application in the Fenton reaction.

This study investigates the ability of formic acid, hydrazine and hydroxylamine to act as H(2) substitutes in conducting phenol degradation by Fenton reaction using in situ generated hydrogen peroxide. The processes were performed with semi-heterogeneous (Pd/Al(2)O(3)+soluble Fe(2+)) and fully heterogeneous (FePd/Al(2)O(3)) catalytic systems under ambient conditions. In contrast to bulk H(2)O(2) production conditions, hydrazine is able to produce H(2)O(2)in situ followed by phenol degradation using Pd/Al(2)O(3)+Fe(2+) at pH 3 without the need for halide ions.

Simultaneous in situ generation of hydrogen peroxide and Fenton reaction over Pd-Fe catalysts.

High mineralization degree of organic compounds can be achieved by a novel environmentally-friendly full heterogeneous Pd-Fe catalytic system, which involves in situ generation of hydrogen peroxide from formic acid and oxygen, and oxidation of organic compounds by Fenton process in a one-pot reaction.