Protective effects of coffee against induction of DNA damage and pre-neoplastic foci by aflatoxin B₁.

Scope: Aim of the study was to investigate the protective properties of coffee towards aflatoxin B₁ (AFB₁) induced formation of pre-neoplastic hepatic foci and the identification of the constituents and molecular mechanisms that account for these effects.

Materials And Methods: Rats consumed three different brews and were subsequently treated with AFB₁ (0.75 mg/kg b.

Cholesterol-raising diterpenes in types of coffee commonly consumed in Singapore, Indonesia and India and associations with blood lipids: a survey and cross sectional study.

Background: To measure the content of cholesterol-raising diterpenes in coffee sold at the retailer level in Singapore, Indonesia and India and to determine the relationship of coffee consumption with lipid levels in a population-based study in Singapore.

Methods: Survey and cross-sectional study in local coffee shops in Singapore, Indonesia and India to measure the diterpene content in coffee, and a population-based study in Singapore to examine the relationship of coffee consumption and blood lipid levels. Interviews and coffee samples (n=27) were collected from coffee shops in Singapore, Indonesia and India.