Publications by authors named "Sandra Bizic"
Cytogenetics of agnogenic myeloid metaplasia: a study of 61 patients.
Cancer Genet Cytogenet
February 2007
Article Synopsis
- Agnogenic myeloid metaplasia (AMM), also known as idiopathic myelofibrosis, is a chronic disorder that affects bone marrow, leading to fibrosis and blood abnormalities.
- Cytogenetic studies reveal that about 41% of patients have chromosomal abnormalities, with trisomy 8 being the most frequent, along with various changes to chromosomes 12, 13, 18, and 20.
- The research identified new chromosomal abnormalities, including rare balanced translocations and instances of near-tetraploidy, suggesting a complex genetic landscape in AMM that extends beyond commonly known abnormalities.