Publications by authors named "Sandra Beltran-Higuera"

Article Synopsis
  • Infections significantly impact pediatric health worldwide, prompting the Staphylo Research Network to study pediatric patients in Colombia between 2018 and 2021, focusing on their epidemiological and microbiological characteristics.
  • The study analyzed 8,157 culture isolations from 20 centers, noting that methicillin-sensitive Staphylococcus aureus (MSSA) was more common than methicillin-resistant Staphylococcus aureus (MRSA), particularly in different regional hospitals.
  • Findings highlight that while MSSA was dominant, regional variations in MRSA prevalence exist, and most strains showed susceptibility to common antibiotics, emphasizing the need for ongoing infection monitoring in children.
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Objective: To describe the clinical and epidemiological characteristics of newborn infants with SARS-CoV-2 infection notified in the Colombian Public Health Surveillance System.

Design: This epidemiological descriptive analysis was conducted using the data of all cases of newborn infants with confirmed SARS-CoV-2 infection notified in the surveillance system. Absolute frequencies and central tendency measures were calculated and a bivariate analysis comparing variables of interest with symptomatic and asymptomatic disease was performed.

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Objective: Clinical practice guidelines (CPG) worldwide help steer the management of early-onset neonatal sepsis (EONS). These documents typically discourage the use of risk assessment tools. However, prior work has shown that the Kaiser Permanente calculator (Early-Onset Sepsis Calculator [EOScalc]) could be a useful tool in EONS risk assessment.

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Article Synopsis
  • - PCVs have helped reduce pneumonia in children, with Colombia starting mass vaccination using PCV10 in 2012, leading to the comparison of pneumonia cases before (2008-2011) and after (2014-2019) vaccination.
  • - The study analyzed 370 cases revealing a significant drop in occurrences of serotypes 1 and 14, while serotypes 19A, 3, and 6A surged, indicating more serious cases needing increased hospital care and longer antibiotic treatment.
  • - Findings suggest that PCV10 decreased specific serotypes but allowed for the rise of more severe strains, emphasizing the need for transitioning to a more effective vaccine like PCV13 to combat evolving pneumonia challenges.
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Article Synopsis
  • The study examines differences in clinical, laboratory, and imaging outcomes between methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-susceptible S. aureus (MSSA) infections in pediatric patients in Bogotá, Colombia.
  • It analyzed 551 pediatric cases from 2014 to 2018, finding that MRSA was linked to more severe infections, especially in cases like bacteremia, osteoarticular infections, and pneumonia.
  • Results suggest that traditional risk factors for MRSA may also apply to MSSA infections, indicating a need for broader understanding and treatment approaches.
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