Background/aim: Enhanced recovery after surgery (ERAS) protocol is adopted in clinical practice worldwide, but a lack of evidence for measurable benefits after upper gastrointestinal (GI) surgeries can be detected especially regarding early oral feeding.
Patients And Methods: A propensity score-matching study was conducted at the Department of Surgery of the University of Pécs between January 2020 and December 2023. The study included patients who underwent upper GI cancer surgery and were treated according to an early oral feeding protocol (EOF).
Some studies have used physical techniques for the assessment of bone structure and composition. However, very few studies applied multiple techniques, such as those described below, at the same time. The aim of our study was to determine the chemical and mineralogical/organic composition of bovine tibial bone samples using geophysical/geochemical reference techniques.
View Article and Find Full Text PDFInorganic fertilizers are routinely used in large scale crop production for the supplementation of nitrogen, phosphorus, and potassium in nutrient poor soil. To explore metabolic changes in tomato plants grown on humic sand under different nutritional conditions, matrix-assisted laser desorption ionization (MALDI) mass spectrometry was utilized for the analysis of xylem sap. Variations in the abundances of metabolites and oligosaccharides, including free -glycans (FNGs), were determined.
View Article and Find Full Text PDFKidney transplantation is the gold-standard therapy for end-stage renal disease. However, in the early postoperative period following allograft kidney transplantation, insufficient graft function presents a diagnostic challenge to clinicians. Ischemic damage to the graft and/or an early autoimmune rejection may cause a decrease in function.
View Article and Find Full Text PDFAccurate characterisation of gastrointestinal stromal tumours (GIST) is important for prognosis and the choice of targeted therapies. Histologically the diagnosis relies on positive immunostaining of tumours for KIT (CD117) and DOG1. Here we report that GISTs also abundantly express the type 3 Sarco/Endoplasmic Reticulum Calcium ATPase (SERCA3).
View Article and Find Full Text PDFThis study aimed to evaluate different commercial diets (Otohime C1, Aller Futura (AF), Biomar Inicio Plus (BIP)) and one experimental feed (EF) in terms of their effectiveness as post-larval diets for indoor weaned largemouth bass, LMB (). Key variations in the content of nutritive values were monounsaturated fatty acid (MUFA) and highly unsaturated FA (HUFA) ω3. Fish were fed with one of four tested diets from the 33rd to the 40th day post-hatch (DPH).
View Article and Find Full Text PDFA 25-week experiment was undertaken to explore the effect of partial replacement of dietary fishmeal (FM) with black soldier fly meal () (BS), mealworm meal () (MW), and a 1 : 1 mixture of both insect meals (BSMW) on fillet quality in African catfish (). A total of 96 fish with an average initial body weight of 248 ± 28 g were stocked into a recirculating aquaculture system and fed in four different dietary groups (control, BS, MW, and BSMW). No mortality was recorded in any of the groups.
View Article and Find Full Text PDFPrevious studies have established that endogenous inorganic polysulfides have significant biological actions activating the Transient Receptor Potential Ankyrin 1 (TRPA1) receptor. Organic polysulfides exert similar effects, but they are much more stable molecules, therefore these compounds are more suitable as drugs. In this study, we aimed to better understand the mechanism of action of organic polysulfides by identification of their binding site on the TRPA1 receptor.
View Article and Find Full Text PDFIntroduction: Indocyanine green is a fluorescent dye, the use of which is becoming more and more widespread in different areas of surgery. Several international studies deal with the dye's usefulness in intraoperative angiography, the localization of tumors, the more precise identification of anatomical structures, the detection of lymph nodes and lymph ducts, etc. The application of the dye is safe, but a suitable equipment park is required for its use, which entails relatively high costs.
View Article and Find Full Text PDFA six-week experiment was carried out to test the effects of total (100%) and partial (50%) replacement of fish meal in the diet of African catfish growers with black soldier fly (B) meal, yellow mealworm (M) meal, and a 1:1 combination of both (BM) on the production and health of fish. A total of 420 fish with an average initial body weight of 200 ± 0.5 g were randomly distributed in triplicate to seven diet groups (C, B50, B100, M50, M100, BM50, and BM100, respectively).
View Article and Find Full Text PDFA digestibility trial was conducted with African catfish hybrid juveniles in order to determine the apparent digestibility coefficients (ADCs) of different nutrients. The experimental diets contained defatted black soldier fly (BSL), yellow mealworm (MW), or fully fat blue bottle fly (BBF) meals, in a 70 : 30 ratio between the control diet and the tested insect meals. The indirect method for the digestibility study was performed using 0.
View Article and Find Full Text PDFIntroduction: The authors audited the outcomes of various surgical interventions employed to fix the dislocations of the acromioclavicular joint in their unit. This resulted in changing their method to treat this condition.
Objective: Finding a technique that results in the best functional stability of the injured joint while preserving its physiological function.
The aim of this study was metagenomics analyses of acquired antibiotic-resistance genes (ARGs) in the intestinal microbiome of two important food-animal species in Hungary from a One Health perspective. Intestinal content samples were collected from 12 domestic pigs () and from a common carp (). Shotgun metagenomic sequencing of DNA purified from the intestinal samples was performed on the Illumina platform.
View Article and Find Full Text PDFPharmaceuticals (Basel)
January 2022
Transient Receptor Potential Ankyrin 1 (TRPA1) has been reported to influence neuroinflammation and lymphocyte function. We analysed the immune phenotype and activation characteristics of TRPA1-deficient mice (knockout-KO) generated by targeted deletion of the pore-loop domain of the ion channel. We compared TRPA1 mRNA and protein expression in monocyte and lymphocyte subpopulations isolated from primary and secondary lymphatic organs of wild type (WT) and KO mice.
View Article and Find Full Text PDFTransient receptor potential ankyrin 1 (TRPA1), a nonselective cation channel, contributes to several (patho)physiological processes. Smell loss is an early sign in several neurodegenerative disorders, such as multiple sclerosis, Parkinson's and Alzheimer's diseases; therefore, we focused on its role in olfaction and social behaviour with the aim to reveal its potential therapeutic use. The presence of mRNA was studied along the olfactory tract of mice by combined RNAscope in situ hybridisation and immunohistochemistry.
View Article and Find Full Text PDFWe studied the effect of different magnitudes (7000 PSI (48.26 MPa), 8000 PSI (55.16 MPa), and 9000 PSI (62.
View Article and Find Full Text PDFThe micro-basins of the Chibunga and Guano rivers are located within the sub-basin of the Chambo River, which starts at the thaw of the Chimborazo, crosses the cities of Guano and Riobamba, and ends in the Chambo River. These rivers are considered fluvial hydrological forces and geological limits of the aquifer, located in this sub-basin. For this reason, our investigation addressed the field capacity in the micro-basins of Chibunga and Guano rivers, to determine the maximum retention potential, i.
View Article and Find Full Text PDFSomatostatin receptor subtype 4 (SST) has been shown to mediate analgesic, antidepressant and anti-inflammatory functions without endocrine actions; therefore, it is proposed to be a novel target for drug development. To overcome the species differences of SST receptor expression and function between humans and mice, we generated an SST humanized mouse line to serve as a translational animal model for preclinical research. A transposon vector containing the and reporter gene construct driven by the regulatory elements were created.
View Article and Find Full Text PDFMeasuring the effect of herbicides on the natural environment is essential to secure sustainable agriculture practices. Amount of carbon dioxide released by soil microorganisms (soil respiration) is one of the most important soil health indicators, known so far. In this paper we present a comprehensive quantifying study, in which we measured the effect of 14 herbicides on soil respiration over 16 years, from 1991 to 2017, at Debrecen-Látókép Plant Cultivation Experimental Station.
View Article and Find Full Text PDFIntroduction: Hypertension (SBP/DBP > 130/80 mmHg) is a leading risk factor for cardiovascular disease worldwide.
Aim: To determine the prevalence of hypertension in a homeless community during an interprofessional education (IPE)-based health fair.
Methods: Homeless participants were recruited between August 2019-September 2019.
Nitrogen (N) is a crop macronutrient of major importance, which affects both plant growth and yield. In this paper we discuss the humus content (%) and various soluble N forms (NO , total N, nitrate-N, ammonium-N, and organic nitrogen) available in humus sand soil samples originating from the Pallag Experimental Station of Horticulture at the University of Debrecen, Hungary. We found 45.
View Article and Find Full Text PDFAlthough knowledge on glycan biosynthesis and processing is continuously maturing, there are still a limited number of studies that examine biological functions of N-glycan structures in plants, which remain virtually unknown. Here, the statistical correlation between nutrient (nitrogen) deficiency symptoms of crops and changes in 8-aminopyrene-1,3,6-trisulfonic acid (APTS)-labeled complex type free oligosaccharides is reported. While deficiency symptoms are predicted by multispectral images and Kjeldahl digestion, APTS-labeled complex type free oligosaccharides are identified by their glucose unit (GU) values in tomato xylem sap, using capillary electrophoresis with laser induced fluorescence detection (CE-LIF).
View Article and Find Full Text PDFIntroduction: Low back pain is a major factor that influences both society and economy. In Hungary, 21% of the population suffers from low back pain or back pain, and six out of ten take medication for the disease. Therapy is complex and no single method has been proved effectively to treat this disease.
View Article and Find Full Text PDF