Case report: A case of undiagnosed cannabinoid hyperemesis syndrome in rural part of Nepal.

Introduction: and importance: Cannabinoid, a widely used recreational drug worldwide. In Nepal, it is found easily and has multiple used as well as misused as a psychoactive substance. Despite having anti emetic property of Marijuana, chronic use of the substance can lead to cyclic vomiting syndrome due to effect in central nervous system and gastrointestinal system.

Cutaneous larva migrans: A case report successfully treated with albendazole.

Introduction: Cutaneous larva migrans (CLM) is helminthic infection that is mostly found in tropical and subtropical areas [1]. It is commonly seen with those who have contact with soil that is contaminated by cat and dog's hookworm larvae. CLM present as erythematous, serpiginous, pruritic cutaneous eruption that is caused by accidental percutaneous penetration and subsequent migration of larvae.

A retrospective study of COVID during pregnancy and the outcome of vaginal delivery.

Introduction: SARS-CoV, MERS-CoV, and SARS-CoV-2, later named coronavirus disease 2019 (COVID-19), are three highly pathogenic and lethal human coronaviruses that have arisen in the last two decades. Pregnant women have a higher risk due to a special state of immunosuppression. However, there is no proof that pregnant women and their babies are more vulnerable to infection, as data is limited.

Steroid as double edged sword; a catastrophic event in the rural part of Nepal.

Introduction And Importance: Cushing's syndrome is a rare condition caused by the long-term glucocorticoid exposure. The clinical picture is variable in severity and presentation. All form of steroid use (parenteral, topical, inhalational as well as additive in herbal and other formulations) are responsible for causing iatrogenic Cushing syndrome.

Diagnostic camouflage: A case report on Latent autoimmune diabetics of adulthood.

Introduction And Importance: Latent autoimmune diabetes of adulthood is an autoimmune disease sharing similarities of type 1 and type 2 diabetics. It is also known as type 1.5 diabetes in adults.

Case reports: Persistent hiccup as an atypical presentation of COVID-19 infection in a vaccinated subject.

Introduction: and Importance: COVID-19 have wide array of clinical manifestation involving both respiratory and non-respiratory symptoms including neurological symptoms. Hiccups is the involuntary and spasmodic movement of the diaphragm and the intercoastal muscle that leads to the closure of the glottis and limitation of breathing in air.

Case Presentation: We present a case of a 72-year old SARS COV-2 positive male with hypertension who have persistent hiccup.

Case report: Paradoxical manifestation of covid 19 induced thyroiditis in the unvaccinated patient.

Introduction And Importance: Subacute thyroiditis (SAT) is a self-limiting viral or post-viral thyroid illness with triphasic clinical history of thyrotoxicosis, hypothyroidism and restoration to normal thyroid function. COVID-19 have wide range of clinical manifestation involving both respiratory and non-respiratory symptoms. Subacute Thyroiditis is one of the emerging symptoms of COVID-19 infection.

Tapia's syndrome in post-operative patient following orotracheal intubation.

Introduction: Tapia's syndrome is a rare condition that manifest due to unilateral extracranial nerve extension of cranial nerve 10 and 12 which occurred as a rare complication of Orotracheal Intubation in patient undergoing Laparoscopic appendectomy.

Case Presentation: A 30 year old male, a known case of normal variant Right bundle branch block and Gilbert syndrome underwent orotracheal intubation prior to general anesthesia for emergency laparoscopic appendectomy. Postoperatively while assessing the patient there was deviation of tongue on left side.

Case report: Hyperthyroid hypokalemic periodic paralysis.

Introduction And Importance: HHPP is a rare type of hypokalemic PP that can occur when there is hyperthyroidism.Thyrotoxic periodic paralysis is due to increased influx of potassium into skeletal muscle cells which leads to profound hypokalemia and paralysis. Insulin and Epinephrine are also responsible for stimulating the Na-K-ATPase pumps which are over expressed during hyperthyroid state.