Effects of a stepwise, structured LDL-C lowering strategy in patients post-acute coronary syndrome.

Objective: Low-density lipoprotein cholesterol (LDL-C) lowering constitutes a cornerstone of secondary prevention of atherosclerotic cardiovascular disease (ASCVD), yet a considerable number of patients do not achieve guideline-recommended LDL‑C targets. The 2016 European guidelines recommended titration of LDL‑C lowering medication in a set number of steps, starting with oral medication. We aimed to investigate the effects of this stepwise approach in post-acute coronary syndrome (ACS) patients.

Slender versus conventional approach reduces post-procedural upper extremity dysfunction after transradial coronary procedures.

Aims: We compared the incidence of post-procedural radial artery occlusion (RAO) and upper extremity dysfunction (UED), in patients undergoing conventional versus slender transradial (TRA) coronary procedures.

Methods And Results: UED was assessed by the QuickDASH, before conventional (i.e.

The Effect of Shear Force on Skin Viability in Patients with Type 2 Diabetes.

Background: Shear is a major risk factor in the development of diabetic foot ulcers, but its effect on the skin of patients with type 2 diabetes mellitus (DM) remains to be elucidated. The aim was to determine skin responses to shear in DM patients with and without diabetic polyneuropathy (DNP).

Methods: The forearm skin was loaded with 14.